Lessons from a pandemic

Several interventions have been used around the world trying to contain the SARS-CoV-2 pandemic, such as quarantine, prohibition of mass demonstrations, isolation of sick people, tracing of virus carriers, semi-containment, promotion of barrier gestures, development of rapid self-tests and vaccines...

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Main Authors: Yves Eggli, Valentin Rousson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLOS Global Public Health
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021850/?tool=EBI
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author Yves Eggli
Valentin Rousson
author_facet Yves Eggli
Valentin Rousson
author_sort Yves Eggli
collection DOAJ
description Several interventions have been used around the world trying to contain the SARS-CoV-2 pandemic, such as quarantine, prohibition of mass demonstrations, isolation of sick people, tracing of virus carriers, semi-containment, promotion of barrier gestures, development of rapid self-tests and vaccines among others. We propose a simple model to evaluate the potential impact of such interventions. A model for the reproduction number of an infectious disease including three main contexts of infection (indoor mass events, public indoor activities and household) and seven parameters is considered. We illustrate how these parameters could be obtained from the literature or from expert assumptions, and we apply the model to describe 20 scenarios that can typically occur during the different phases of a pandemic. This model provides a useful framework for better understanding and communicating the effects of different (combinations of) possible interventions, while encouraging constant updating of expert assumptions to better match reality. This simple approach will bring more transparency and public support to help governments to think, decide, evaluate and adjust what to do during a pandemic.
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spelling doaj.art-4620fc7161da4b19bf429a253a5d5bde2023-09-03T10:08:52ZengPublic Library of Science (PLoS)PLOS Global Public Health2767-33752022-01-0127Lessons from a pandemicYves EggliValentin RoussonSeveral interventions have been used around the world trying to contain the SARS-CoV-2 pandemic, such as quarantine, prohibition of mass demonstrations, isolation of sick people, tracing of virus carriers, semi-containment, promotion of barrier gestures, development of rapid self-tests and vaccines among others. We propose a simple model to evaluate the potential impact of such interventions. A model for the reproduction number of an infectious disease including three main contexts of infection (indoor mass events, public indoor activities and household) and seven parameters is considered. We illustrate how these parameters could be obtained from the literature or from expert assumptions, and we apply the model to describe 20 scenarios that can typically occur during the different phases of a pandemic. This model provides a useful framework for better understanding and communicating the effects of different (combinations of) possible interventions, while encouraging constant updating of expert assumptions to better match reality. This simple approach will bring more transparency and public support to help governments to think, decide, evaluate and adjust what to do during a pandemic.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021850/?tool=EBI
spellingShingle Yves Eggli
Valentin Rousson
Lessons from a pandemic
PLOS Global Public Health
title Lessons from a pandemic
title_full Lessons from a pandemic
title_fullStr Lessons from a pandemic
title_full_unstemmed Lessons from a pandemic
title_short Lessons from a pandemic
title_sort lessons from a pandemic
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021850/?tool=EBI
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