The analgesic activity of Mentha piperita (MP) leaves extract
In the present work, the antinociceptive action was assayed in several experiment models in mice, Hot plate, writhing and formalin test. The alcoholic extract of MP leaves at a dose of 150mg/kg B.W and 300 mg/kgB.W showed antinociceptive effects in different methods, where the dose of 300 mg/kg B.W...
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| Format: | Article |
| Language: | English |
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University of Baghdad, College of Veterinary Medicine
2010-12-01
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| Series: | The Iraqi Journal of Veterinary Medicine |
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| Online Access: | https://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/633 |
| _version_ | 1818385170965725184 |
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| author | Ahmed Najim abed saleh |
| author_facet | Ahmed Najim abed saleh |
| author_sort | Ahmed Najim abed saleh |
| collection | DOAJ |
| description | In the present work, the antinociceptive action was assayed in several experiment models in mice, Hot plate, writhing and formalin test. The alcoholic extract of MP leaves at a dose of 150mg/kg B.W and 300 mg/kgB.W showed antinociceptive effects in different methods, where the dose of 300 mg/kg B.W showed significant reduction of the nociception by acetic acid. In the formalin test, the extract (300mg/kg B.W) also significantly reduced painful stimulus in both phases of the test. Treatment with extract (300mg/kg B.W) when given orally produced significant increase of the reaction time in hot plate test. These results showed that the leaves extract of MP contain active analgesic principles acting both centrally and peripherally. |
| first_indexed | 2024-12-14T03:33:54Z |
| format | Article |
| id | doaj.art-4622f7185ddc464986e422a85b21ee00 |
| institution | Directory Open Access Journal |
| issn | 1609-5693 2410-7409 |
| language | English |
| last_indexed | 2024-12-14T03:33:54Z |
| publishDate | 2010-12-01 |
| publisher | University of Baghdad, College of Veterinary Medicine |
| record_format | Article |
| series | The Iraqi Journal of Veterinary Medicine |
| spelling | doaj.art-4622f7185ddc464986e422a85b21ee002022-12-21T23:18:40ZengUniversity of Baghdad, College of Veterinary MedicineThe Iraqi Journal of Veterinary Medicine1609-56932410-74092010-12-0134210.30539/iraqijvm.v34i2.633The analgesic activity of Mentha piperita (MP) leaves extractAhmed Najim abed saleh0College of Veterinary Medicine, Baghdad UniversityIn the present work, the antinociceptive action was assayed in several experiment models in mice, Hot plate, writhing and formalin test. The alcoholic extract of MP leaves at a dose of 150mg/kg B.W and 300 mg/kgB.W showed antinociceptive effects in different methods, where the dose of 300 mg/kg B.W showed significant reduction of the nociception by acetic acid. In the formalin test, the extract (300mg/kg B.W) also significantly reduced painful stimulus in both phases of the test. Treatment with extract (300mg/kg B.W) when given orally produced significant increase of the reaction time in hot plate test. These results showed that the leaves extract of MP contain active analgesic principles acting both centrally and peripherally.https://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/633analgesic, menthe piperita,leaveextract. |
| spellingShingle | Ahmed Najim abed saleh The analgesic activity of Mentha piperita (MP) leaves extract The Iraqi Journal of Veterinary Medicine analgesic, menthe piperita,leaveextract. |
| title | The analgesic activity of Mentha piperita (MP) leaves extract |
| title_full | The analgesic activity of Mentha piperita (MP) leaves extract |
| title_fullStr | The analgesic activity of Mentha piperita (MP) leaves extract |
| title_full_unstemmed | The analgesic activity of Mentha piperita (MP) leaves extract |
| title_short | The analgesic activity of Mentha piperita (MP) leaves extract |
| title_sort | analgesic activity of mentha piperita mp leaves extract |
| topic | analgesic, menthe piperita,leaveextract. |
| url | https://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/633 |
| work_keys_str_mv | AT ahmednajimabedsaleh theanalgesicactivityofmenthapiperitampleavesextract AT ahmednajimabedsaleh analgesicactivityofmenthapiperitampleavesextract |