Function of cell adhesion molecules in differentiation of ray sensory neurons in <i>C. elegans</i>

AbstractFor proper functioning of the nervous system, it is crucial that neurons find their appropriate partners and build the correct neural connection patterns. Although cell adhesion molecules (CAMs) have been studied for many years as essential players in neural connections, we h...

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Bibliographic Details
Main Authors: Naoko Sakai, Peter Sun, Byunghyuk Kim, Scott W Emmons
Format: Article
Language:English
Published: Oxford University Press 2022-12-01
Series:G3: Genes, Genomes, Genetics
Online Access:https://academic.oup.com/g3journal/article-lookup/doi/10.1093/g3journal/jkac338
Description
Summary:AbstractFor proper functioning of the nervous system, it is crucial that neurons find their appropriate partners and build the correct neural connection patterns. Although cell adhesion molecules (CAMs) have been studied for many years as essential players in neural connections, we have yet to unravel the code by which CAMs encode synaptic specificity. We analyzed the effects of mutations in CAM genes on the morphology and synapses of a set of sensory neurons in the Caenorhabditis elegans
ISSN:2160-1836