Function of cell adhesion molecules in differentiation of ray sensory neurons in <i>C. elegans</i>

AbstractFor proper functioning of the nervous system, it is crucial that neurons find their appropriate partners and build the correct neural connection patterns. Although cell adhesion molecules (CAMs) have been studied for many years as essential players in neural connections, we h...

Full description

Bibliographic Details
Main Authors: Naoko Sakai, Peter Sun, Byunghyuk Kim, Scott W Emmons
Format: Article
Language:English
Published: Oxford University Press 2022-12-01
Series:G3: Genes, Genomes, Genetics
Online Access:https://academic.oup.com/g3journal/article-lookup/doi/10.1093/g3journal/jkac338
_version_ 1797788935397572608
author Naoko Sakai
Peter Sun
Byunghyuk Kim
Scott W Emmons
author_facet Naoko Sakai
Peter Sun
Byunghyuk Kim
Scott W Emmons
author_sort Naoko Sakai
collection DOAJ
description AbstractFor proper functioning of the nervous system, it is crucial that neurons find their appropriate partners and build the correct neural connection patterns. Although cell adhesion molecules (CAMs) have been studied for many years as essential players in neural connections, we have yet to unravel the code by which CAMs encode synaptic specificity. We analyzed the effects of mutations in CAM genes on the morphology and synapses of a set of sensory neurons in the Caenorhabditis elegans
first_indexed 2024-03-13T01:42:36Z
format Article
id doaj.art-4623167d0c2a48ca83a3a65200e53a22
institution Directory Open Access Journal
issn 2160-1836
language English
last_indexed 2024-03-13T01:42:36Z
publishDate 2022-12-01
publisher Oxford University Press
record_format Article
series G3: Genes, Genomes, Genetics
spelling doaj.art-4623167d0c2a48ca83a3a65200e53a222023-07-03T11:09:46ZengOxford University PressG3: Genes, Genomes, Genetics2160-18362022-12-0113310.1093/g3journal/jkac338Function of cell adhesion molecules in differentiation of ray sensory neurons in <i>C. elegans</i> Naoko Sakai0https://orcid.org/0000-0002-6311-5281Peter Sun1Byunghyuk Kim2https://orcid.org/0000-0002-2220-4173Scott W Emmons3Department of Genetics, Albert Einstein College of Medicine, Bronx, New York 162-8666, USADepartment of Genetics, Albert Einstein College of Medicine, Bronx, New York 162-8666, USADepartment of Genetics, Albert Einstein College of Medicine, Bronx, New York 162-8666, USADepartment of Genetics, Albert Einstein College of Medicine, Bronx, New York 162-8666, USA AbstractFor proper functioning of the nervous system, it is crucial that neurons find their appropriate partners and build the correct neural connection patterns. Although cell adhesion molecules (CAMs) have been studied for many years as essential players in neural connections, we have yet to unravel the code by which CAMs encode synaptic specificity. We analyzed the effects of mutations in CAM genes on the morphology and synapses of a set of sensory neurons in the Caenorhabditis eleganshttps://academic.oup.com/g3journal/article-lookup/doi/10.1093/g3journal/jkac338
spellingShingle Naoko Sakai
Peter Sun
Byunghyuk Kim
Scott W Emmons
Function of cell adhesion molecules in differentiation of ray sensory neurons in <i>C. elegans</i>
G3: Genes, Genomes, Genetics
title Function of cell adhesion molecules in differentiation of ray sensory neurons in <i>C. elegans</i>
title_full Function of cell adhesion molecules in differentiation of ray sensory neurons in <i>C. elegans</i>
title_fullStr Function of cell adhesion molecules in differentiation of ray sensory neurons in <i>C. elegans</i>
title_full_unstemmed Function of cell adhesion molecules in differentiation of ray sensory neurons in <i>C. elegans</i>
title_short Function of cell adhesion molecules in differentiation of ray sensory neurons in <i>C. elegans</i>
title_sort function of cell adhesion molecules in differentiation of ray sensory neurons in i c elegans i
url https://academic.oup.com/g3journal/article-lookup/doi/10.1093/g3journal/jkac338
work_keys_str_mv AT naokosakai functionofcelladhesionmoleculesindifferentiationofraysensoryneuronsinicelegansi
AT petersun functionofcelladhesionmoleculesindifferentiationofraysensoryneuronsinicelegansi
AT byunghyukkim functionofcelladhesionmoleculesindifferentiationofraysensoryneuronsinicelegansi
AT scottwemmons functionofcelladhesionmoleculesindifferentiationofraysensoryneuronsinicelegansi