Function of cell adhesion molecules in differentiation of ray sensory neurons in <i>C. elegans</i>
AbstractFor proper functioning of the nervous system, it is crucial that neurons find their appropriate partners and build the correct neural connection patterns. Although cell adhesion molecules (CAMs) have been studied for many years as essential players in neural connections, we h...
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Format: | Article |
Language: | English |
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Oxford University Press
2022-12-01
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Series: | G3: Genes, Genomes, Genetics |
Online Access: | https://academic.oup.com/g3journal/article-lookup/doi/10.1093/g3journal/jkac338 |
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author | Naoko Sakai Peter Sun Byunghyuk Kim Scott W Emmons |
author_facet | Naoko Sakai Peter Sun Byunghyuk Kim Scott W Emmons |
author_sort | Naoko Sakai |
collection | DOAJ |
description |
AbstractFor proper functioning of the nervous system, it is crucial that neurons find their appropriate partners and build the correct neural connection patterns. Although cell adhesion molecules (CAMs) have been studied for many years as essential players in neural connections, we have yet to unravel the code by which CAMs encode synaptic specificity. We analyzed the effects of mutations in CAM genes on the morphology and synapses of a set of sensory neurons in the Caenorhabditis elegans |
first_indexed | 2024-03-13T01:42:36Z |
format | Article |
id | doaj.art-4623167d0c2a48ca83a3a65200e53a22 |
institution | Directory Open Access Journal |
issn | 2160-1836 |
language | English |
last_indexed | 2024-03-13T01:42:36Z |
publishDate | 2022-12-01 |
publisher | Oxford University Press |
record_format | Article |
series | G3: Genes, Genomes, Genetics |
spelling | doaj.art-4623167d0c2a48ca83a3a65200e53a222023-07-03T11:09:46ZengOxford University PressG3: Genes, Genomes, Genetics2160-18362022-12-0113310.1093/g3journal/jkac338Function of cell adhesion molecules in differentiation of ray sensory neurons in <i>C. elegans</i> Naoko Sakai0https://orcid.org/0000-0002-6311-5281Peter Sun1Byunghyuk Kim2https://orcid.org/0000-0002-2220-4173Scott W Emmons3Department of Genetics, Albert Einstein College of Medicine, Bronx, New York 162-8666, USADepartment of Genetics, Albert Einstein College of Medicine, Bronx, New York 162-8666, USADepartment of Genetics, Albert Einstein College of Medicine, Bronx, New York 162-8666, USADepartment of Genetics, Albert Einstein College of Medicine, Bronx, New York 162-8666, USA AbstractFor proper functioning of the nervous system, it is crucial that neurons find their appropriate partners and build the correct neural connection patterns. Although cell adhesion molecules (CAMs) have been studied for many years as essential players in neural connections, we have yet to unravel the code by which CAMs encode synaptic specificity. We analyzed the effects of mutations in CAM genes on the morphology and synapses of a set of sensory neurons in the Caenorhabditis eleganshttps://academic.oup.com/g3journal/article-lookup/doi/10.1093/g3journal/jkac338 |
spellingShingle | Naoko Sakai Peter Sun Byunghyuk Kim Scott W Emmons Function of cell adhesion molecules in differentiation of ray sensory neurons in <i>C. elegans</i> G3: Genes, Genomes, Genetics |
title | Function of cell adhesion molecules in differentiation of ray sensory neurons in <i>C. elegans</i>
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title_full | Function of cell adhesion molecules in differentiation of ray sensory neurons in <i>C. elegans</i>
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title_fullStr | Function of cell adhesion molecules in differentiation of ray sensory neurons in <i>C. elegans</i>
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title_full_unstemmed | Function of cell adhesion molecules in differentiation of ray sensory neurons in <i>C. elegans</i>
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title_short | Function of cell adhesion molecules in differentiation of ray sensory neurons in <i>C. elegans</i>
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title_sort | function of cell adhesion molecules in differentiation of ray sensory neurons in i c elegans i |
url | https://academic.oup.com/g3journal/article-lookup/doi/10.1093/g3journal/jkac338 |
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