A threonyl-tRNA synthetase-mediated translation initiation machinery
The initiation of translation is a highly regulated process that contributes to specific gene expression programs. Here the authors find that, in vertebrate, threonyl-tRNA synthetase (TRS) can act as a scaffold for the initiation machinery to stimulate the translation of a specific set of mRNAs.
Bibliographic Details
| Main Authors: |
Seung Jae Jeong,
Shinhye Park,
Loi T. Nguyen,
Jungwon Hwang,
Eun-Young Lee,
Hoi-Khoanh Giong,
Jeong-Soo Lee,
Ina Yoon,
Ji-Hyun Lee,
Jong Hyun Kim,
Hoi Kyoung Kim,
Doyeun Kim,
Won Suk Yang,
Seon-Young Kim,
Chan Yong Lee,
Kweon Yu,
Nahum Sonenberg,
Myung Hee Kim,
Sunghoon Kim |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2019-03-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-019-09086-0
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