A standard burn model using rats
Experimental burn models are always needed, being essential for burn research. In the present study, we describe a standard Fischer F-344 rat burn model, in which burns are produced with a heated brass bar. The animals were anesthetized with ketamine (90 mg/kg). After the burns, they were resuscitat...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
1999-10-01
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| Series: | Acta Cirúrgica Brasileira |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86501999000400009&tlng=en |
| _version_ | 1818490185634021376 |
|---|---|
| author | Tufi Neder Meyer Alcino Lázaro da Silva |
| author_facet | Tufi Neder Meyer Alcino Lázaro da Silva |
| author_sort | Tufi Neder Meyer |
| collection | DOAJ |
| description | Experimental burn models are always needed, being essential for burn research. In the present study, we describe a standard Fischer F-344 rat burn model, in which burns are produced with a heated brass bar. The animals were anesthetized with ketamine (90 mg/kg). After the burns, they were resuscitated with saline. Burns ranging from 26% to 30% of total body surface area resulted in a 62.5 % mortality rate after 25 days. This model is an additional option for those interested in burn research. |
| first_indexed | 2024-12-10T17:13:52Z |
| format | Article |
| id | doaj.art-4628a15978c74dcfa317226401e839c0 |
| institution | Directory Open Access Journal |
| issn | 0102-8650 |
| language | English |
| last_indexed | 2024-12-10T17:13:52Z |
| publishDate | 1999-10-01 |
| publisher | Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
| record_format | Article |
| series | Acta Cirúrgica Brasileira |
| spelling | doaj.art-4628a15978c74dcfa317226401e839c02022-12-22T01:40:11ZengSociedade Brasileira para o Desenvolvimento da Pesquisa em CirurgiaActa Cirúrgica Brasileira0102-86501999-10-0114410.1590/S0102-86501999000400009A standard burn model using ratsTufi Neder Meyer0Alcino Lázaro da Silva1Universidade do Vale do Rio VerdeUniversidade Federal de Minas GeraisExperimental burn models are always needed, being essential for burn research. In the present study, we describe a standard Fischer F-344 rat burn model, in which burns are produced with a heated brass bar. The animals were anesthetized with ketamine (90 mg/kg). After the burns, they were resuscitated with saline. Burns ranging from 26% to 30% of total body surface area resulted in a 62.5 % mortality rate after 25 days. This model is an additional option for those interested in burn research.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86501999000400009&tlng=enBurnsDisease Models, Animal |
| spellingShingle | Tufi Neder Meyer Alcino Lázaro da Silva A standard burn model using rats Acta Cirúrgica Brasileira Burns Disease Models, Animal |
| title | A standard burn model using rats |
| title_full | A standard burn model using rats |
| title_fullStr | A standard burn model using rats |
| title_full_unstemmed | A standard burn model using rats |
| title_short | A standard burn model using rats |
| title_sort | standard burn model using rats |
| topic | Burns Disease Models, Animal |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86501999000400009&tlng=en |
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