Primary hypothyroidism with exuberant dermatological manifestations,
Abstract Thyroid hormone has effects on the skin. Patients with hypothyroidism have changes such as dry, scaly and rough skin. Increase carotene in the dermis becomes a yellowish tone to the skin of the patient with hypothyroidism. There is an increase in capillary cycle (anagen phase) and nail grow...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Dermatologia
2020-11-01
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| Series: | Anais Brasileiros de Dermatologia |
| Subjects: | |
| Online Access: | http://www.scielo.br/pdf/abd/v95n6/0365-0596-abd-95-06-0721.pdf |
| _version_ | 1818365876103020544 |
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| author | Thadeu Santos Silva Gustavo Baptista de Almeida Faro Márcia Gabrielle Bonfim Cortes Vitória Regina Pedreira de Almeida Rego |
| author_facet | Thadeu Santos Silva Gustavo Baptista de Almeida Faro Márcia Gabrielle Bonfim Cortes Vitória Regina Pedreira de Almeida Rego |
| author_sort | Thadeu Santos Silva |
| collection | DOAJ |
| description | Abstract Thyroid hormone has effects on the skin. Patients with hypothyroidism have changes such as dry, scaly and rough skin. Increase carotene in the dermis becomes a yellowish tone to the skin of the patient with hypothyroidism. There is an increase in capillary cycle (anagen phase) and nail growth and a reduction in eccrine gland secretion. It is a case of primary hypothyroidism with nail manifestations associated with dermatologic disorders and successful treatment with levothyroxine. Receptors for thyroid hormone have already been found in keratinocytes, fibroblasts, hair follicles and sebaceous glands. Genes responsive to thyroid hormones and elements of the hypothalamic–pituitary–thyroid axis were identified on the skin. This report highlights the importance of cutaneous manifestations as markers of thyroid disease. |
| first_indexed | 2024-12-13T22:27:13Z |
| format | Article |
| id | doaj.art-462b7d11357a414282f6302f71721321 |
| institution | Directory Open Access Journal |
| issn | 0365-0596 |
| language | English |
| last_indexed | 2024-12-13T22:27:13Z |
| publishDate | 2020-11-01 |
| publisher | Sociedade Brasileira de Dermatologia |
| record_format | Article |
| series | Anais Brasileiros de Dermatologia |
| spelling | doaj.art-462b7d11357a414282f6302f717213212022-12-21T23:29:10ZengSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia0365-05962020-11-0195672172310.1016/j.abd.2019.07.010Primary hypothyroidism with exuberant dermatological manifestations,Thadeu Santos Silvahttps://orcid.org/0000-0002-3259-059XGustavo Baptista de Almeida Farohttps://orcid.org/0000-0002-8777-1259Márcia Gabrielle Bonfim Corteshttps://orcid.org/0000-0001-5693-8856Vitória Regina Pedreira de Almeida Regohttps://orcid.org/0000-0002-5947-3713Abstract Thyroid hormone has effects on the skin. Patients with hypothyroidism have changes such as dry, scaly and rough skin. Increase carotene in the dermis becomes a yellowish tone to the skin of the patient with hypothyroidism. There is an increase in capillary cycle (anagen phase) and nail growth and a reduction in eccrine gland secretion. It is a case of primary hypothyroidism with nail manifestations associated with dermatologic disorders and successful treatment with levothyroxine. Receptors for thyroid hormone have already been found in keratinocytes, fibroblasts, hair follicles and sebaceous glands. Genes responsive to thyroid hormones and elements of the hypothalamic–pituitary–thyroid axis were identified on the skin. This report highlights the importance of cutaneous manifestations as markers of thyroid disease.http://www.scielo.br/pdf/abd/v95n6/0365-0596-abd-95-06-0721.pdfHypothyroidismThyroid diseasesThyroid glandThyroid hormonesThyroxine |
| spellingShingle | Thadeu Santos Silva Gustavo Baptista de Almeida Faro Márcia Gabrielle Bonfim Cortes Vitória Regina Pedreira de Almeida Rego Primary hypothyroidism with exuberant dermatological manifestations, Anais Brasileiros de Dermatologia Hypothyroidism Thyroid diseases Thyroid gland Thyroid hormones Thyroxine |
| title | Primary hypothyroidism with exuberant dermatological manifestations, |
| title_full | Primary hypothyroidism with exuberant dermatological manifestations, |
| title_fullStr | Primary hypothyroidism with exuberant dermatological manifestations, |
| title_full_unstemmed | Primary hypothyroidism with exuberant dermatological manifestations, |
| title_short | Primary hypothyroidism with exuberant dermatological manifestations, |
| title_sort | primary hypothyroidism with exuberant dermatological manifestations |
| topic | Hypothyroidism Thyroid diseases Thyroid gland Thyroid hormones Thyroxine |
| url | http://www.scielo.br/pdf/abd/v95n6/0365-0596-abd-95-06-0721.pdf |
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