Toksisitas Ekstrak Daun Sirih Merah pada Tikus Putih Penderita Diabetes Melitus (TOXICITY OF RED BETEL EXTRACT IN DIABETIC WHITE RAT )
The aim of this research was to study the toxicity of red betel (Piper crocatum) extract in diabeticwhite rat based on ALT and AST activities. This research used 20 male white rats, which randomlydivided into five groups, P1: given only aqua; P2: given alloxan 120mg/kg bw; P3: given alloxan 120 mg/...
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| Format: | Article |
| Language: | English |
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Universitas Udayana
2013-12-01
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| Series: | Jurnal Veteriner |
| Subjects: | |
| Online Access: | http://ojs.unud.ac.id/index.php/jvet/article/view/7689 |
| _version_ | 1818676203874156544 |
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| author | Anak Agung Sagung Kendran Ketut Tono Pasek Gelgel Ni Wayan Linda Pertiwi Made Suma Anthara Anak Agung Gde Oka Dharmayuda Luh Dewi Anggreni |
| author_facet | Anak Agung Sagung Kendran Ketut Tono Pasek Gelgel Ni Wayan Linda Pertiwi Made Suma Anthara Anak Agung Gde Oka Dharmayuda Luh Dewi Anggreni |
| author_sort | Anak Agung Sagung Kendran |
| collection | DOAJ |
| description | The aim of this research was to study the toxicity of red betel (Piper crocatum) extract in diabeticwhite rat based on ALT and AST activities. This research used 20 male white rats, which randomlydivided into five groups, P1: given only aqua; P2: given alloxan 120mg/kg bw; P3: given alloxan 120 mg/kgbw and red betel leaf extract 50 mg/kg bw; P4: given alloxan 120 mg/kg bw and red betel leaf extract 100mg/kg bw; P5: given alloxan 120 mg/kg bw and glibenclamide suspension 1 mg/kg bw. ALT and ASTactivities were measured by using reflovet plus Machine. The collected data were analyzed by usinganalysis of covariance. The result showed no significant effect (P>0.05) was observed on giving red betelleaf extract in diabetic white rat for ALT and AST activities. It can be concluded that red betel leaf extractis potential for diabetic treatment in white rat and it is not toxic for the rat’s ALT and AST activities. |
| first_indexed | 2024-12-17T08:39:45Z |
| format | Article |
| id | doaj.art-462c476eff804a5096f0d14627b8a8e2 |
| institution | Directory Open Access Journal |
| issn | 1411-8327 2477-5665 |
| language | English |
| last_indexed | 2024-12-17T08:39:45Z |
| publishDate | 2013-12-01 |
| publisher | Universitas Udayana |
| record_format | Article |
| series | Jurnal Veteriner |
| spelling | doaj.art-462c476eff804a5096f0d14627b8a8e22022-12-21T21:56:23ZengUniversitas UdayanaJurnal Veteriner1411-83272477-56652013-12-011446631Toksisitas Ekstrak Daun Sirih Merah pada Tikus Putih Penderita Diabetes Melitus (TOXICITY OF RED BETEL EXTRACT IN DIABETIC WHITE RAT )Anak Agung Sagung Kendran0Ketut Tono Pasek GelgelNi Wayan Linda PertiwiMade Suma AntharaAnak Agung Gde Oka DharmayudaLuh Dewi AnggreniBagian Klinik Hewan, Fakultas Kedokteran Hewan, Universitas Udayana, BaliThe aim of this research was to study the toxicity of red betel (Piper crocatum) extract in diabeticwhite rat based on ALT and AST activities. This research used 20 male white rats, which randomlydivided into five groups, P1: given only aqua; P2: given alloxan 120mg/kg bw; P3: given alloxan 120 mg/kgbw and red betel leaf extract 50 mg/kg bw; P4: given alloxan 120 mg/kg bw and red betel leaf extract 100mg/kg bw; P5: given alloxan 120 mg/kg bw and glibenclamide suspension 1 mg/kg bw. ALT and ASTactivities were measured by using reflovet plus Machine. The collected data were analyzed by usinganalysis of covariance. The result showed no significant effect (P>0.05) was observed on giving red betelleaf extract in diabetic white rat for ALT and AST activities. It can be concluded that red betel leaf extractis potential for diabetic treatment in white rat and it is not toxic for the rat’s ALT and AST activities.http://ojs.unud.ac.id/index.php/jvet/article/view/7689Red betel leaf, diabetes mellitus, ALT and AST activity |
| spellingShingle | Anak Agung Sagung Kendran Ketut Tono Pasek Gelgel Ni Wayan Linda Pertiwi Made Suma Anthara Anak Agung Gde Oka Dharmayuda Luh Dewi Anggreni Toksisitas Ekstrak Daun Sirih Merah pada Tikus Putih Penderita Diabetes Melitus (TOXICITY OF RED BETEL EXTRACT IN DIABETIC WHITE RAT ) Jurnal Veteriner Red betel leaf, diabetes mellitus, ALT and AST activity |
| title | Toksisitas Ekstrak Daun Sirih Merah pada Tikus Putih Penderita Diabetes Melitus (TOXICITY OF RED BETEL EXTRACT IN DIABETIC WHITE RAT ) |
| title_full | Toksisitas Ekstrak Daun Sirih Merah pada Tikus Putih Penderita Diabetes Melitus (TOXICITY OF RED BETEL EXTRACT IN DIABETIC WHITE RAT ) |
| title_fullStr | Toksisitas Ekstrak Daun Sirih Merah pada Tikus Putih Penderita Diabetes Melitus (TOXICITY OF RED BETEL EXTRACT IN DIABETIC WHITE RAT ) |
| title_full_unstemmed | Toksisitas Ekstrak Daun Sirih Merah pada Tikus Putih Penderita Diabetes Melitus (TOXICITY OF RED BETEL EXTRACT IN DIABETIC WHITE RAT ) |
| title_short | Toksisitas Ekstrak Daun Sirih Merah pada Tikus Putih Penderita Diabetes Melitus (TOXICITY OF RED BETEL EXTRACT IN DIABETIC WHITE RAT ) |
| title_sort | toksisitas ekstrak daun sirih merah pada tikus putih penderita diabetes melitus toxicity of red betel extract in diabetic white rat |
| topic | Red betel leaf, diabetes mellitus, ALT and AST activity |
| url | http://ojs.unud.ac.id/index.php/jvet/article/view/7689 |
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