Intermittent Ethanol during Adolescence Leads to Lasting Behavioral Changes in Adulthood and Alters Gene Expression and Histone Methylation in the PFC
Adolescents primarily consume alcohol in binges, which can be particularly harmful to the developing frontal cortex and increase risk for an adult alcohol use disorder. We conducted a study investigating immediate and long lasting changes to the prefrontal cortex (PFC) transcriptome to determine the...
Main Authors: | Jennifer T. Wolstenholme, Tariq Mahmood, Guy M. Harris, Shahroze Abbas, Michael F. Miles |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2017-09-01
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Series: | Frontiers in Molecular Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fnmol.2017.00307/full |
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