Progress in immune pathogenesis and targeted therapy of alopecia areata
Alopecia areata is a common clinical non-cicatricial alopecia. Alopecia totalis and generalized alopecia may occur in severe cases. The pathogenesis of alopecia areata is complex, and the treatment is faced with many difficulties. The traditional treatment method is not effective for moderate and se...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology
2023-02-01
|
| Series: | Pifu-xingbing zhenliaoxue zazhi |
| Subjects: | |
| Online Access: | http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2023.01.016 |
| _version_ | 1797374081681588224 |
|---|---|
| author | Jiali WANG Dantong CHENG Nana LUO Pingsheng HAO |
| author_facet | Jiali WANG Dantong CHENG Nana LUO Pingsheng HAO |
| author_sort | Jiali WANG |
| collection | DOAJ |
| description | Alopecia areata is a common clinical non-cicatricial alopecia. Alopecia totalis and generalized alopecia may occur in severe cases. The pathogenesis of alopecia areata is complex, and the treatment is faced with many difficulties. The traditional treatment method is not effective for moderate and severe alopecia areata. Therapeutic efficacy varies with patients because of the differences in the pathogenesis. Although patients with generalized alopecia areata usually respond well to the treatment, the risk of recurrence is high. Patients with generalized alopecia areata are often subject to psychological stress. With the wide use of biological agents and small molecular drugs in atopic dermatitis and psoriasis, targeted treatment for alopecia areata is becoming an important treatment method. This article reviews the progress of immunopathogenesis and targeted treatment of alopecia areata, and explores new ideas for the treatment. |
| first_indexed | 2024-03-08T18:59:44Z |
| format | Article |
| id | doaj.art-46322695733b4aee9f20a129532164cb |
| institution | Directory Open Access Journal |
| issn | 1674-8468 |
| language | zho |
| last_indexed | 2024-03-08T18:59:44Z |
| publishDate | 2023-02-01 |
| publisher | editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology |
| record_format | Article |
| series | Pifu-xingbing zhenliaoxue zazhi |
| spelling | doaj.art-46322695733b4aee9f20a129532164cb2023-12-28T06:52:31Zzhoeditoiral office of Journal of Diagnosis and Therapy on Dermato-venereologyPifu-xingbing zhenliaoxue zazhi1674-84682023-02-01301838810.3969/j.issn.1674-8468.2023.01.016Progress in immune pathogenesis and targeted therapy of alopecia areataJiali WANGDantong CHENGNana LUOPingsheng HAOAlopecia areata is a common clinical non-cicatricial alopecia. Alopecia totalis and generalized alopecia may occur in severe cases. The pathogenesis of alopecia areata is complex, and the treatment is faced with many difficulties. The traditional treatment method is not effective for moderate and severe alopecia areata. Therapeutic efficacy varies with patients because of the differences in the pathogenesis. Although patients with generalized alopecia areata usually respond well to the treatment, the risk of recurrence is high. Patients with generalized alopecia areata are often subject to psychological stress. With the wide use of biological agents and small molecular drugs in atopic dermatitis and psoriasis, targeted treatment for alopecia areata is becoming an important treatment method. This article reviews the progress of immunopathogenesis and targeted treatment of alopecia areata, and explores new ideas for the treatment.http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2023.01.016alopecia areatapathogenesistargeted therapybiological agentssmall molecule drugs |
| spellingShingle | Jiali WANG Dantong CHENG Nana LUO Pingsheng HAO Progress in immune pathogenesis and targeted therapy of alopecia areata Pifu-xingbing zhenliaoxue zazhi alopecia areata pathogenesis targeted therapy biological agents small molecule drugs |
| title | Progress in immune pathogenesis and targeted therapy of alopecia areata |
| title_full | Progress in immune pathogenesis and targeted therapy of alopecia areata |
| title_fullStr | Progress in immune pathogenesis and targeted therapy of alopecia areata |
| title_full_unstemmed | Progress in immune pathogenesis and targeted therapy of alopecia areata |
| title_short | Progress in immune pathogenesis and targeted therapy of alopecia areata |
| title_sort | progress in immune pathogenesis and targeted therapy of alopecia areata |
| topic | alopecia areata pathogenesis targeted therapy biological agents small molecule drugs |
| url | http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2023.01.016 |
| work_keys_str_mv | AT jialiwang progressinimmunepathogenesisandtargetedtherapyofalopeciaareata AT dantongcheng progressinimmunepathogenesisandtargetedtherapyofalopeciaareata AT nanaluo progressinimmunepathogenesisandtargetedtherapyofalopeciaareata AT pingshenghao progressinimmunepathogenesisandtargetedtherapyofalopeciaareata |