Tilapia-Head Chondroitin Sulfate Protects against Nonalcoholic Fatty Liver Disease via Modulating the Gut–Liver Axis in High-Fat-Diet-Fed C57BL/6 Mice

Tilapia-Head Chondroitin Sulfate Protects against Nonalcoholic Fatty Liver Disease via Modulating the Gut–Liver Axis in High-Fat-Diet-Fed C57BL/6 Mice

We isolated and characterized tilapia-head chondroitin sulfate (TH-CS) and explored its biological activity and mechanisms of action as an oral supplement for nonalcoholic fatty liver disease (NAFLD) induced by a high-fat diet (HFD) in mice. The results showed that treatment with TH-CS for 8 weeks a...

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Bibliographic Details
Main Authors: Hui Yu, Xiangzhou Yi, Xia Gao, Jun Ji, Zhongyuan Liu, Guanghua Xia, Chuan Li, Xueying Zhang, Xuanri Shen
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Foods
Subjects:
tilapia head
chondroitin sulfate
nonalcoholic fatty liver disease
gut–liver axis
Online Access:https://www.mdpi.com/2304-8158/11/7/922

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