Radiotherapy Combined with PD-1 Inhibition Increases NK Cell Cytotoxicity towards Nasopharyngeal Carcinoma Cells

Radiotherapy Combined with PD-1 Inhibition Increases NK Cell Cytotoxicity towards Nasopharyngeal Carcinoma Cells

Background: Nasopharyngeal carcinoma (NPC) in endemic regions and younger patients is characterized by a prominent lymphomononuclear infiltration. Radiation is the principal therapeutic modality for patients with NPC. Recent data suggest that the efficacy of radiotherapy in various cancers can be au...

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Bibliographic Details
Main Authors: Anna Makowska, Nora Lelabi, Christina Nothbaum, Lian Shen, Pierre Busson, Tram Thi Bao Tran, Michael Eble, Udo Kontny
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cells
Subjects:
nasopharyngeal carcinoma
natural killer cells
programmed cell death ligand 1
radiotherapy
nuclear factor kappa B
interferon-beta
Online Access:https://www.mdpi.com/2073-4409/10/9/2458

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