AMLVaran: a software approach to implement variant analysis of targeted NGS sequencing data in an oncological care setting

AMLVaran: a software approach to implement variant analysis of targeted NGS sequencing data in an oncological care setting

Abstract Background Next-Generation Sequencing (NGS) enables large-scale and cost-effective sequencing of genetic samples in order to detect genetic variants. After successful use in research-oriented projects, NGS is now entering clinical practice. Consequently, variant analysis is increasingly imp...

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Bibliographic Details
Main Authors: Christian Wünsch, Henrik Banck, Carsten Müller-Tidow, Martin Dugas
Format: Article
Language:English
Published: BMC 2020-02-01
Series:BMC Medical Genomics
Subjects:
Genomics
NGS sequencing
Variant calling
Variant annotation
Variant filtering
Variant interpretation
Online Access:https://doi.org/10.1186/s12920-020-0668-3

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