Protein residue network analysis reveals fundamental properties of the human coagulation factor VIII

Protein residue network analysis reveals fundamental properties of the human coagulation factor VIII

Abstract Hemophilia A is an X-linked inherited blood coagulation disorder caused by the production and circulation of defective coagulation factor VIII protein. People living with this condition receive either prophylaxis or on-demand treatment, and approximately 30% of patients develop inhibitor an...

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Bibliographic Details
Main Authors: Tiago J. S. Lopes, Ricardo Rios, Tatiane Nogueira, Rodrigo F. Mello
Format: Article
Language:English
Published: Nature Portfolio 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-92201-3

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