Primary Myelofibrosis with Mesenteric Extramedullary Haematopoiesis
Primary myelofibrosis or chronic idiopathic myelofibrosis is a myeloproliferative neoplasm characterized by proliferation of abnormal haematopoietic stem cells in bone marrow resulting in replacement of marrow with fibrotic scar tissue. Extramedullary Haematopoiesis (EMH) as a compensatory phenome...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2018-12-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/12321/37276_CE[Ra]_F(P)_PF1(A_SHU)%20_PFA(SHU)_PB(A_SHU)_PN(P).pdf |
| Summary: | Primary myelofibrosis or chronic idiopathic myelofibrosis is a myeloproliferative neoplasm characterized by proliferation of
abnormal haematopoietic stem cells in bone marrow resulting in replacement of marrow with fibrotic scar tissue. Extramedullary
Haematopoiesis (EMH) as a compensatory phenomenon in myelofibrosis can lead to hepatosplenomegaly with diffuse organ
infiltration or focal deposits. Peritoneal involvement of EMH is rare and can present with peritoneal or serosal implants which can
mimic malignancy. We present a case of diffuse peritoneal /mesenteric extramedullary haematopoiesis with hepatosplenomegaly
as an initial presentation in patient of idiopathic myelofibrosis. |
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| ISSN: | 2249-782X 0973-709X |