l-theanine: A potential multifaceted natural bioactive amide as health supplement

Natural bioactive compounds from plants are of great importance in modern therapeutics, which are used to prepare antibiotics, growth supplements or some other therapeutics. l-theanine is such a bioactive amide amino acid presented in different plants and fungi, especially in tea. Theanine has influ...

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Main Authors: Rajsekhar Adhikary, Vivekananda Mandal
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-09-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2221169117308420
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author Rajsekhar Adhikary
Vivekananda Mandal
author_facet Rajsekhar Adhikary
Vivekananda Mandal
author_sort Rajsekhar Adhikary
collection DOAJ
description Natural bioactive compounds from plants are of great importance in modern therapeutics, which are used to prepare antibiotics, growth supplements or some other therapeutics. l-theanine is such a bioactive amide amino acid presented in different plants and fungi, especially in tea. Theanine has influential effects on lifestyle associated diseases, such as diabetes, cardiovascular disorders, hypertension, stress relief, tumor suppression, menstruation and liver injury. This amino acid can maintain normal sleep and improve memory function and nullify effect of the neurotoxins. The rate of bioavailability and its medium of ingestion in the body is one of the great concerns for its additional antioxidant properties. Pharmacokinetics of the bioactive compound and its mode of action are described herewith. The biosynthesis and industrial synthesis are also reviewed to promote accelerated production of this bioactive compound in the pharmaceutical industries.
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spelling doaj.art-46416c390044440c81dac449b74427e92022-12-21T21:58:58ZengWolters Kluwer Medknow PublicationsAsian Pacific Journal of Tropical Biomedicine2221-16912017-09-017984284810.1016/j.apjtb.2017.08.005l-theanine: A potential multifaceted natural bioactive amide as health supplementRajsekhar AdhikaryVivekananda MandalNatural bioactive compounds from plants are of great importance in modern therapeutics, which are used to prepare antibiotics, growth supplements or some other therapeutics. l-theanine is such a bioactive amide amino acid presented in different plants and fungi, especially in tea. Theanine has influential effects on lifestyle associated diseases, such as diabetes, cardiovascular disorders, hypertension, stress relief, tumor suppression, menstruation and liver injury. This amino acid can maintain normal sleep and improve memory function and nullify effect of the neurotoxins. The rate of bioavailability and its medium of ingestion in the body is one of the great concerns for its additional antioxidant properties. Pharmacokinetics of the bioactive compound and its mode of action are described herewith. The biosynthesis and industrial synthesis are also reviewed to promote accelerated production of this bioactive compound in the pharmaceutical industries.http://www.sciencedirect.com/science/article/pii/S2221169117308420Bioactive amideBioavailabilityl-theanineLifestyle associated diseasesPharmacokinetics
spellingShingle Rajsekhar Adhikary
Vivekananda Mandal
l-theanine: A potential multifaceted natural bioactive amide as health supplement
Asian Pacific Journal of Tropical Biomedicine
Bioactive amide
Bioavailability
l-theanine
Lifestyle associated diseases
Pharmacokinetics
title l-theanine: A potential multifaceted natural bioactive amide as health supplement
title_full l-theanine: A potential multifaceted natural bioactive amide as health supplement
title_fullStr l-theanine: A potential multifaceted natural bioactive amide as health supplement
title_full_unstemmed l-theanine: A potential multifaceted natural bioactive amide as health supplement
title_short l-theanine: A potential multifaceted natural bioactive amide as health supplement
title_sort l theanine a potential multifaceted natural bioactive amide as health supplement
topic Bioactive amide
Bioavailability
l-theanine
Lifestyle associated diseases
Pharmacokinetics
url http://www.sciencedirect.com/science/article/pii/S2221169117308420
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AT vivekanandamandal ltheanineapotentialmultifacetednaturalbioactiveamideashealthsupplement