Naturally Occurring Endocrine Disorders in Non-Human Primates: A Comprehensive Review

Literature concerning veterinary medicine of non-human primates is continuously updated, yet endocrine disorders remain underreported. While case or survey reports of individual endocrinopathies are available, a comprehensive review is not. An exhaustive literature search on this subject via widely...

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Main Authors: Jaco Bakker, Melissa A. de la Garza
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Animals
Subjects:
Online Access:https://www.mdpi.com/2076-2615/12/4/407
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author Jaco Bakker
Melissa A. de la Garza
author_facet Jaco Bakker
Melissa A. de la Garza
author_sort Jaco Bakker
collection DOAJ
description Literature concerning veterinary medicine of non-human primates is continuously updated, yet endocrine disorders remain underreported. While case or survey reports of individual endocrinopathies are available, a comprehensive review is not. An exhaustive literature search on this subject via widely used academic search systems, (e.g., Google Scholar, PubMed, BioOne complete and Web of Science), and peer-reviewed publications, proceedings, and newsletters was performed. Selected major endocrine entities will be described with emphasis on clinical signs, morphologic appearances, concomitant diseases, as well as available treatment options. Mostly, no clinical signs were noted and on gross pathology, the endocrine organs were unremarkable. An endocrine-related diagnosis was frequently made as an incidental finding after standard histopathological examination. During the review, the pancreas represented the most affected endocrine organ and diabetes mellitus represented the most clinically significant disorder. Currently, no standard procedure for diagnosing, monitoring, or treating endocrine disorders in non-human primates exists.
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spelling doaj.art-4642cf41081044bcb557d945f75a68902023-11-23T18:24:35ZengMDPI AGAnimals2076-26152022-02-0112440710.3390/ani12040407Naturally Occurring Endocrine Disorders in Non-Human Primates: A Comprehensive ReviewJaco Bakker0Melissa A. de la Garza1Biomedical Primate Research Centre (BPRC), Animal Science Department (ASD), 2288GJ Rijswijk, The NetherlandsIndependent Researcher, San Antonio, TX 78216, USALiterature concerning veterinary medicine of non-human primates is continuously updated, yet endocrine disorders remain underreported. While case or survey reports of individual endocrinopathies are available, a comprehensive review is not. An exhaustive literature search on this subject via widely used academic search systems, (e.g., Google Scholar, PubMed, BioOne complete and Web of Science), and peer-reviewed publications, proceedings, and newsletters was performed. Selected major endocrine entities will be described with emphasis on clinical signs, morphologic appearances, concomitant diseases, as well as available treatment options. Mostly, no clinical signs were noted and on gross pathology, the endocrine organs were unremarkable. An endocrine-related diagnosis was frequently made as an incidental finding after standard histopathological examination. During the review, the pancreas represented the most affected endocrine organ and diabetes mellitus represented the most clinically significant disorder. Currently, no standard procedure for diagnosing, monitoring, or treating endocrine disorders in non-human primates exists.https://www.mdpi.com/2076-2615/12/4/407adrenalendocrine disordershormoneneoplasiaNHPpancreas
spellingShingle Jaco Bakker
Melissa A. de la Garza
Naturally Occurring Endocrine Disorders in Non-Human Primates: A Comprehensive Review
Animals
adrenal
endocrine disorders
hormone
neoplasia
NHP
pancreas
title Naturally Occurring Endocrine Disorders in Non-Human Primates: A Comprehensive Review
title_full Naturally Occurring Endocrine Disorders in Non-Human Primates: A Comprehensive Review
title_fullStr Naturally Occurring Endocrine Disorders in Non-Human Primates: A Comprehensive Review
title_full_unstemmed Naturally Occurring Endocrine Disorders in Non-Human Primates: A Comprehensive Review
title_short Naturally Occurring Endocrine Disorders in Non-Human Primates: A Comprehensive Review
title_sort naturally occurring endocrine disorders in non human primates a comprehensive review
topic adrenal
endocrine disorders
hormone
neoplasia
NHP
pancreas
url https://www.mdpi.com/2076-2615/12/4/407
work_keys_str_mv AT jacobakker naturallyoccurringendocrinedisordersinnonhumanprimatesacomprehensivereview
AT melissaadelagarza naturallyoccurringendocrinedisordersinnonhumanprimatesacomprehensivereview