Perinatal triphenyl phosphate exposure induces metabolic dysfunctions through the EGFR/ERK/AKT signaling pathway: Mechanistic in vitro and in vivo studies

Perinatal triphenyl phosphate exposure induces metabolic dysfunctions through the EGFR/ERK/AKT signaling pathway: Mechanistic in vitro and in vivo studies

Triphenyl phosphate (TPhP), a widely used organophosphate-flame retardant, is ubiquitously found in household environments and may adversely affect human health. Evidence indicates that TPhP exposure causes metabolic dysfunctions in vivo; however, the underlying mechanism of such adverse effects has...

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Bibliographic Details
Main Authors: Phum Tachachartvanich, Xylina Rusit, Jason Tong, Chanapa Mann, Michele A. La Merrill
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Triphenyl phosphate
Insulin resistance
Metabolic health
Epidermal growth factor receptor
Adipogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323012605

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