Osteopontin Activation and Microcalcification in Venous Grafts Can Be Modulated by Dexamethasone

Background: Osteopontin has been implicated in vascular calcification formation and vein graft intimal hyperplasia, and its expression can be triggered by pro-inflammatory activation of cells. The role of osteopontin and the temporal formation of microcalcification in vein grafts is poorly understoo...

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Bibliographic Details
Main Authors: Liam W. McQueen, Shameem S. Ladak, Georgia R. Layton, Kerry Wadey, Sarah J. George, Gianni D. Angelini, Gavin J. Murphy, Mustafa Zakkar
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/12/22/2627