Experience in the Treatment of Irritable Bowel Syndrome Developed after a New Coronavirus Infection (COVID-19)

Aim. To study the effectiveness of Kolofort® (affinally purified antibodies to tumor necrosis factor α, to the brain-specific protein S-100 and to histamine) in patients with various variants of irritable bowel syndrome (IBS) that developed after a new coronavirus infection (COVID-19).Materials and...

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Main Author: R. G. Myazin
Format: Article
Language:Russian
Published: Gastro LLC 2022-05-01
Series:Российский журнал гастроэнтерологии, гепатологии, колопроктологии
Subjects:
Online Access:https://www.gastro-j.ru/jour/article/view/716
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author R. G. Myazin
author_facet R. G. Myazin
author_sort R. G. Myazin
collection DOAJ
description Aim. To study the effectiveness of Kolofort® (affinally purified antibodies to tumor necrosis factor α, to the brain-specific protein S-100 and to histamine) in patients with various variants of irritable bowel syndrome (IBS) that developed after a new coronavirus infection (COVID-19).Materials and methods. Clinical and laboratory data of 32 patients with IBS who had a history of COVID-19 pneumonia were analyzed. Course therapy with Kolofort® is prescribed according to the standard scheme for 3 months. Before and after treatment, the dynamics of the symptoms of IBS was assessed according to the questionnaire, the dynamics of anxiety was assessed according to the Hamilton scale.Results. There were a statistically significant decrease in the severity of IBS symptoms (normalization of the consistency of the stool, cessation of flatulence, a decrease in abdominal  pain; p < 0.05) and a decrease in anxiety after the end of treatment.Conclusions. Kolofort® may be effective in eliminating the symptoms of post-infectious  IBS and anxiety that developed after COVID-19.
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spelling doaj.art-46479a9a59f94386af91f62c1439bd9d2024-03-25T16:53:10ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732022-05-01321414510.22416/1382-4376-2022-32-1-41-45461Experience in the Treatment of Irritable Bowel Syndrome Developed after a New Coronavirus Infection (COVID-19)R. G. Myazin0Volgograd State Medical University of the Ministry of Health of the Russian FederationAim. To study the effectiveness of Kolofort® (affinally purified antibodies to tumor necrosis factor α, to the brain-specific protein S-100 and to histamine) in patients with various variants of irritable bowel syndrome (IBS) that developed after a new coronavirus infection (COVID-19).Materials and methods. Clinical and laboratory data of 32 patients with IBS who had a history of COVID-19 pneumonia were analyzed. Course therapy with Kolofort® is prescribed according to the standard scheme for 3 months. Before and after treatment, the dynamics of the symptoms of IBS was assessed according to the questionnaire, the dynamics of anxiety was assessed according to the Hamilton scale.Results. There were a statistically significant decrease in the severity of IBS symptoms (normalization of the consistency of the stool, cessation of flatulence, a decrease in abdominal  pain; p < 0.05) and a decrease in anxiety after the end of treatment.Conclusions. Kolofort® may be effective in eliminating the symptoms of post-infectious  IBS and anxiety that developed after COVID-19.https://www.gastro-j.ru/jour/article/view/716coronavirus infectionirritable bowel syndromediagnosistreatmentkolofort®
spellingShingle R. G. Myazin
Experience in the Treatment of Irritable Bowel Syndrome Developed after a New Coronavirus Infection (COVID-19)
Российский журнал гастроэнтерологии, гепатологии, колопроктологии
coronavirus infection
irritable bowel syndrome
diagnosis
treatment
kolofort®
title Experience in the Treatment of Irritable Bowel Syndrome Developed after a New Coronavirus Infection (COVID-19)
title_full Experience in the Treatment of Irritable Bowel Syndrome Developed after a New Coronavirus Infection (COVID-19)
title_fullStr Experience in the Treatment of Irritable Bowel Syndrome Developed after a New Coronavirus Infection (COVID-19)
title_full_unstemmed Experience in the Treatment of Irritable Bowel Syndrome Developed after a New Coronavirus Infection (COVID-19)
title_short Experience in the Treatment of Irritable Bowel Syndrome Developed after a New Coronavirus Infection (COVID-19)
title_sort experience in the treatment of irritable bowel syndrome developed after a new coronavirus infection covid 19
topic coronavirus infection
irritable bowel syndrome
diagnosis
treatment
kolofort®
url https://www.gastro-j.ru/jour/article/view/716
work_keys_str_mv AT rgmyazin experienceinthetreatmentofirritablebowelsyndromedevelopedafteranewcoronavirusinfectioncovid19