Vitamin D3 promotes gastric cancer cell autophagy by mediating p53/AMPK/mTOR signaling

Vitamin D3 promotes gastric cancer cell autophagy by mediating p53/AMPK/mTOR signaling

Objective: Vitamin D3 has the general properties of a lipid-soluble vitamin, but is also an active steroid hormone that can regulate the proliferation, apoptosis and differentiation of many tumor cells, and exerts anticancer activity against numerous malignancies. However, the mechanism underlying t...

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Bibliographic Details
Main Authors: Yanan Wang, Qingmin He, Kang Rong, Mingyang Zhu, Xiaoxiao Zhao, Pengyuan Zheng, Yang Mi
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Pharmacology
Subjects:
network pharmacology
molecular docking
vitamin D3
gastric cancer
molecular mechanism
autophagy
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1338260/full

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