Characterization of Flavonoids and Naphthopyranones in Methanol Extracts of Paepalanthus chiquitensis Herzog by HPLC-ESI-IT-MSn and Their Mutagenic Activity

Characterization of Flavonoids and Naphthopyranones in Methanol Extracts of Paepalanthus chiquitensis Herzog by HPLC-ESI-IT-MSn and Their Mutagenic Activity

A HPLC-ESI-IT-MSn method, based on high-performance liquid chromatography coupled to electrospray negative ionization multistage ion trap mass spectrometry, was developed for rapid identification of 24 flavonoid and naphthopyranone compounds. The methanol extracts of the capitulae and scapes of P. c...

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Bibliographic Details
Main Authors: Wagner Vilegas, Lourdes Campaner dos Santos, Paulo Takeo Sano, Samara Fernandes de Souza, Eliana Aparecida Varanda, Paula Karina Boldrin, Fabiana Volpe Zanutto
Format: Article
Language:English
Published: MDPI AG 2012-12-01
Series:Molecules
Subjects:
Paepalanthus
naphthopyranones
flavonoids
mutagenicity
Online Access:http://www.mdpi.com/1420-3049/18/1/244
Description
Summary:A HPLC-ESI-IT-MSn method, based on high-performance liquid chromatography coupled to electrospray negative ionization multistage ion trap mass spectrometry, was developed for rapid identification of 24 flavonoid and naphthopyranone compounds. The methanol extracts of the capitulae and scapes of P. chiquitensis exhibited mutagenic activity in the Salmonella/microsome assay, against strain TA97a.
ISSN:1420-3049

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