Altered T cell memory and effector cell development in chronic lymphatic filarial infection that is independent of persistent parasite antigen.
Chronic lymphatic filarial (LF) infection is associated with suppression of parasite-specific T cell responses that persist even following elimination of infection. While several mechanisms have been implicated in mediating this T cell specific downregulation, a role for alterations in the homeostas...
Main Authors: | Cathy Steel, Thomas B Nutman |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-04-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3084782?pdf=render |
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