Cancer-associated keratinocytes: new members of the microenvironment in head and neck cancer
The tumor microenvironment is a complex ecosystem of malignant and nonmalignant cells and extracellular proteins that work together to enhance tumor progression. We identified a mechanism in which adjacent nonmalignant epithelium enhances invasion of squamous cell carcinoma, thereby expanding the tu...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2021-07-01
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| Series: | Molecular & Cellular Oncology |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/23723556.2021.1933329 |
| _version_ | 1827809332507443200 |
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| author | Erika B. Danella Marcell Costa De Medeiros Nisha J. D’Silva |
| author_facet | Erika B. Danella Marcell Costa De Medeiros Nisha J. D’Silva |
| author_sort | Erika B. Danella |
| collection | DOAJ |
| description | The tumor microenvironment is a complex ecosystem of malignant and nonmalignant cells and extracellular proteins that work together to enhance tumor progression. We identified a mechanism in which adjacent nonmalignant epithelium enhances invasion of squamous cell carcinoma, thereby expanding the tumor microenvironment to include cancer-associated keratinocytes. |
| first_indexed | 2024-03-11T22:39:42Z |
| format | Article |
| id | doaj.art-464ed680de7243a7ae97e5839513f34f |
| institution | Directory Open Access Journal |
| issn | 2372-3556 |
| language | English |
| last_indexed | 2024-03-11T22:39:42Z |
| publishDate | 2021-07-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Molecular & Cellular Oncology |
| spelling | doaj.art-464ed680de7243a7ae97e5839513f34f2023-09-22T09:19:43ZengTaylor & Francis GroupMolecular & Cellular Oncology2372-35562021-07-018410.1080/23723556.2021.19333291933329Cancer-associated keratinocytes: new members of the microenvironment in head and neck cancerErika B. Danella0Marcell Costa De Medeiros1Nisha J. D’Silva2School of Dentistry, University of MichiganSchool of Dentistry, University of MichiganSchool of Dentistry, University of MichiganThe tumor microenvironment is a complex ecosystem of malignant and nonmalignant cells and extracellular proteins that work together to enhance tumor progression. We identified a mechanism in which adjacent nonmalignant epithelium enhances invasion of squamous cell carcinoma, thereby expanding the tumor microenvironment to include cancer-associated keratinocytes.http://dx.doi.org/10.1080/23723556.2021.1933329invasionmetastasistumor recurrencedeleted in malignant brain tumors 1 |
| spellingShingle | Erika B. Danella Marcell Costa De Medeiros Nisha J. D’Silva Cancer-associated keratinocytes: new members of the microenvironment in head and neck cancer Molecular & Cellular Oncology invasion metastasis tumor recurrence deleted in malignant brain tumors 1 |
| title | Cancer-associated keratinocytes: new members of the microenvironment in head and neck cancer |
| title_full | Cancer-associated keratinocytes: new members of the microenvironment in head and neck cancer |
| title_fullStr | Cancer-associated keratinocytes: new members of the microenvironment in head and neck cancer |
| title_full_unstemmed | Cancer-associated keratinocytes: new members of the microenvironment in head and neck cancer |
| title_short | Cancer-associated keratinocytes: new members of the microenvironment in head and neck cancer |
| title_sort | cancer associated keratinocytes new members of the microenvironment in head and neck cancer |
| topic | invasion metastasis tumor recurrence deleted in malignant brain tumors 1 |
| url | http://dx.doi.org/10.1080/23723556.2021.1933329 |
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