Mind the Gap: How Some Viruses Infect Their Hosts
Cryo-electron microscopy (Cryo-EM) and cryo-electron tomography (Cryo-ET) provide structural insights into complex biological processes. The podoviridae are dsDNA containing phage with short, non-contractile tails which nevertheless translocate their DNA into the cytoplasm of their host cells. Liu e...
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| Format: | Article |
| Language: | English |
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MDPI AG
2010-11-01
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| Series: | Viruses |
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| Online Access: | http://www.mdpi.com/1999-4915/2/11/2536/ |
| _version_ | 1811311406663860224 |
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| author | Peter E. Prevelige |
| author_facet | Peter E. Prevelige |
| author_sort | Peter E. Prevelige |
| collection | DOAJ |
| description | Cryo-electron microscopy (Cryo-EM) and cryo-electron tomography (Cryo-ET) provide structural insights into complex biological processes. The podoviridae are dsDNA containing phage with short, non-contractile tails which nevertheless translocate their DNA into the cytoplasm of their host cells. Liu et al. [1] used a combination of cryo-EM and cryo-ET to study the structural changes accompanying infection of P. marinus by the phage P-SSP7 and thereby provide unique molecular insight into the process by which the DNA transits from phage to host during infection. |
| first_indexed | 2024-04-13T10:18:21Z |
| format | Article |
| id | doaj.art-46514348fb8348abb5937e96f71d28d4 |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-04-13T10:18:21Z |
| publishDate | 2010-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-46514348fb8348abb5937e96f71d28d42022-12-22T02:50:37ZengMDPI AGViruses1999-49152010-11-012112536254010.3390/v2112536Mind the Gap: How Some Viruses Infect Their HostsPeter E. PreveligeCryo-electron microscopy (Cryo-EM) and cryo-electron tomography (Cryo-ET) provide structural insights into complex biological processes. The podoviridae are dsDNA containing phage with short, non-contractile tails which nevertheless translocate their DNA into the cytoplasm of their host cells. Liu et al. [1] used a combination of cryo-EM and cryo-ET to study the structural changes accompanying infection of P. marinus by the phage P-SSP7 and thereby provide unique molecular insight into the process by which the DNA transits from phage to host during infection.http://www.mdpi.com/1999-4915/2/11/2536/Cyanophage P-SSP7 phageDNA injectioncryo-electron microscopycryo-electron tomography |
| spellingShingle | Peter E. Prevelige Mind the Gap: How Some Viruses Infect Their Hosts Viruses Cyanophage P-SSP7 phage DNA injection cryo-electron microscopy cryo-electron tomography |
| title | Mind the Gap: How Some Viruses Infect Their Hosts |
| title_full | Mind the Gap: How Some Viruses Infect Their Hosts |
| title_fullStr | Mind the Gap: How Some Viruses Infect Their Hosts |
| title_full_unstemmed | Mind the Gap: How Some Viruses Infect Their Hosts |
| title_short | Mind the Gap: How Some Viruses Infect Their Hosts |
| title_sort | mind the gap how some viruses infect their hosts |
| topic | Cyanophage P-SSP7 phage DNA injection cryo-electron microscopy cryo-electron tomography |
| url | http://www.mdpi.com/1999-4915/2/11/2536/ |
| work_keys_str_mv | AT petereprevelige mindthegaphowsomevirusesinfecttheirhosts |