Acupuncture of different treatment frequency in knee osteoarthritis: a protocol for a pilot randomized clinical trial
Abstract Background This study aims to determine whether 3 sessions per week of acupuncture treatment is superior to 1 session per week of acupuncture treatment for symptomatic outcomes in knee osteoarthritis. Methods/design This is a two parallel-group, assessor-blinded, randomized controlled trial...
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| Format: | Article |
| Language: | English |
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BMC
2019-07-01
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| Series: | Trials |
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| Online Access: | http://link.springer.com/article/10.1186/s13063-019-3528-8 |
| _version_ | 1824005705131098112 |
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| author | Lu-Lu Lin Jian-Feng Tu Jia-Kai Shao Xuan Zou Tian-Qi Wang Li-Qiong Wang Jing-Wen Yang Ning Sun Cun-Zhi Liu |
| author_facet | Lu-Lu Lin Jian-Feng Tu Jia-Kai Shao Xuan Zou Tian-Qi Wang Li-Qiong Wang Jing-Wen Yang Ning Sun Cun-Zhi Liu |
| author_sort | Lu-Lu Lin |
| collection | DOAJ |
| description | Abstract Background This study aims to determine whether 3 sessions per week of acupuncture treatment is superior to 1 session per week of acupuncture treatment for symptomatic outcomes in knee osteoarthritis. Methods/design This is a two parallel-group, assessor-blinded, randomized controlled trial. Sixty patients with knee osteoarthritis (Kellgren–Lawrence grade II or III) will be recruited and randomly allocated to receive 24 or 8 sessions (group M or group L) of acupuncture treatment in a 1:1 ratio. Patients in group M will receive 3 sessions per week of acupuncture for 8 weeks. Patients in group L will receive acupuncture once per week for 8 weeks. The primary outcome is the response rate—the percentage of patients achieving a decrease ≥ 2 points on a numerical rating pain scale and a decrease ≥ 6 points in the Western Ontario and McMaster Universities Osteoarthritis Index function score at 8 weeks compared with baseline. Secondary outcomes include pain, function, overall effect, quality of life, and treatment credibility and expectancy. Discussion Three sessions per week of acupuncture treatment may be superior to 1 session per week of acupuncture treatment for symptomatic outcomes in knee osteoarthritis. Results of the study will be of great importance for the guidelines of clinical therapy. Trial registration Clinicaltrials.gov, NCT03359603. Registered on 1 December 2017. |
| first_indexed | 2024-12-18T20:15:55Z |
| format | Article |
| id | doaj.art-4655e2b8b8a2462b8d8fb47323ae24c3 |
| institution | Directory Open Access Journal |
| issn | 1745-6215 |
| language | English |
| last_indexed | 2024-12-18T20:15:55Z |
| publishDate | 2019-07-01 |
| publisher | BMC |
| record_format | Article |
| series | Trials |
| spelling | doaj.art-4655e2b8b8a2462b8d8fb47323ae24c32022-12-21T20:54:30ZengBMCTrials1745-62152019-07-012011810.1186/s13063-019-3528-8Acupuncture of different treatment frequency in knee osteoarthritis: a protocol for a pilot randomized clinical trialLu-Lu Lin0Jian-Feng Tu1Jia-Kai Shao2Xuan Zou3Tian-Qi Wang4Li-Qiong Wang5Jing-Wen Yang6Ning Sun7Cun-Zhi Liu8School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese MedicineDepartment of Acupuncture and Moxibustion, Beijing Hospital of Traditional Chinese Medicine affiliated to Capital Medical UniversityDepartment of Acupuncture and Moxibustion, Beijing Hospital of Traditional Chinese Medicine affiliated to Capital Medical UniversitySchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese MedicineSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese MedicineSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese MedicineSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese MedicineSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese MedicineSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese MedicineAbstract Background This study aims to determine whether 3 sessions per week of acupuncture treatment is superior to 1 session per week of acupuncture treatment for symptomatic outcomes in knee osteoarthritis. Methods/design This is a two parallel-group, assessor-blinded, randomized controlled trial. Sixty patients with knee osteoarthritis (Kellgren–Lawrence grade II or III) will be recruited and randomly allocated to receive 24 or 8 sessions (group M or group L) of acupuncture treatment in a 1:1 ratio. Patients in group M will receive 3 sessions per week of acupuncture for 8 weeks. Patients in group L will receive acupuncture once per week for 8 weeks. The primary outcome is the response rate—the percentage of patients achieving a decrease ≥ 2 points on a numerical rating pain scale and a decrease ≥ 6 points in the Western Ontario and McMaster Universities Osteoarthritis Index function score at 8 weeks compared with baseline. Secondary outcomes include pain, function, overall effect, quality of life, and treatment credibility and expectancy. Discussion Three sessions per week of acupuncture treatment may be superior to 1 session per week of acupuncture treatment for symptomatic outcomes in knee osteoarthritis. Results of the study will be of great importance for the guidelines of clinical therapy. Trial registration Clinicaltrials.gov, NCT03359603. Registered on 1 December 2017.http://link.springer.com/article/10.1186/s13063-019-3528-8Knee osteoarthritisAcupunctureTreatment frequencyClinical trial |
| spellingShingle | Lu-Lu Lin Jian-Feng Tu Jia-Kai Shao Xuan Zou Tian-Qi Wang Li-Qiong Wang Jing-Wen Yang Ning Sun Cun-Zhi Liu Acupuncture of different treatment frequency in knee osteoarthritis: a protocol for a pilot randomized clinical trial Trials Knee osteoarthritis Acupuncture Treatment frequency Clinical trial |
| title | Acupuncture of different treatment frequency in knee osteoarthritis: a protocol for a pilot randomized clinical trial |
| title_full | Acupuncture of different treatment frequency in knee osteoarthritis: a protocol for a pilot randomized clinical trial |
| title_fullStr | Acupuncture of different treatment frequency in knee osteoarthritis: a protocol for a pilot randomized clinical trial |
| title_full_unstemmed | Acupuncture of different treatment frequency in knee osteoarthritis: a protocol for a pilot randomized clinical trial |
| title_short | Acupuncture of different treatment frequency in knee osteoarthritis: a protocol for a pilot randomized clinical trial |
| title_sort | acupuncture of different treatment frequency in knee osteoarthritis a protocol for a pilot randomized clinical trial |
| topic | Knee osteoarthritis Acupuncture Treatment frequency Clinical trial |
| url | http://link.springer.com/article/10.1186/s13063-019-3528-8 |
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