The value of vestibular graviceptive pathway evaluation in the diagnosis of unilateral peripheral vestibular dysfunction
Abstract Background Evaluation of vestibular graviceptive pathway (VGP) in patients with unilateral peripheral vestibular dysfunction (UPVD) has received increasing attention from researchers. The study aimed to investigate the value of VGP evaluation in the diagnosis of UPVD. Methods Ninety‐five UP...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-07-01
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| Series: | Brain and Behavior |
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| Online Access: | https://doi.org/10.1002/brb3.3055 |
| _version_ | 1827902830947598336 |
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| author | Tong‐tong Zhao Meng‐lu Zhang Yu‐fei Feng Qian‐qian Wang Ning Song Xu Yang Xiao‐hong Ba |
| author_facet | Tong‐tong Zhao Meng‐lu Zhang Yu‐fei Feng Qian‐qian Wang Ning Song Xu Yang Xiao‐hong Ba |
| author_sort | Tong‐tong Zhao |
| collection | DOAJ |
| description | Abstract Background Evaluation of vestibular graviceptive pathway (VGP) in patients with unilateral peripheral vestibular dysfunction (UPVD) has received increasing attention from researchers. The study aimed to investigate the value of VGP evaluation in the diagnosis of UPVD. Methods Ninety‐five UPVD patients were divided into attack and remission phase groups. VGP evaluation‐related indicators, including subjective visual vertical (SVV), subjective visual horizontal (SVH), head tilt, ocular torsion (OT), and skew deviation (SD), were measured, and their correlations with cochleovestibular function test results were analyzed. The possible etiologies of contralesional VGP (c‐VGP) were analyzed. Results Positive rates of SVV, SVH, OT, and SD were significantly higher, and the degrees of SVV, SVH, and OT were significantly greater in the attack phase group than the remission phase group. The sides with abnormal VGP evaluation results were correlated with the sides with hearing loss, abnormal caloric, and video head impulse test (vHIT) results. A total of 14 patients showed c‐VGP, and possible etiologies included contralateral benign paroxysmal positional vertigo (n = 4), bilateral hearing loss (n = 8), bilateral vHIT gain reduction (n = 1), autoimmune diseases (n = 6), vascular risk factors (n = 6), lacunar infarction (n = 3), and endolymphatic hydrops (n = 3). Conclusions Alterations in SVV, SVH, OT, and SD were noted in UPVD patients in different phases, which are presumed to be related to dynamic vestibular compensation; correlations between VGP evaluation results and cochleovestibular function test results indicate that VGP evaluation may be helpful for the diagnosis of the side affected in UPVD; the presence of c‐VGP may be related to bilateral labyrinth lesions or endolymphatic hydrops on the affected side; and the involvement of autoimmune mechanisms also deserves attention. |
| first_indexed | 2024-03-13T00:04:42Z |
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| id | doaj.art-465a04002e2640cca6690162a6e83819 |
| institution | Directory Open Access Journal |
| issn | 2162-3279 |
| language | English |
| last_indexed | 2024-03-13T00:04:42Z |
| publishDate | 2023-07-01 |
| publisher | Wiley |
| record_format | Article |
| series | Brain and Behavior |
| spelling | doaj.art-465a04002e2640cca6690162a6e838192023-07-13T04:43:15ZengWileyBrain and Behavior2162-32792023-07-01137n/an/a10.1002/brb3.3055The value of vestibular graviceptive pathway evaluation in the diagnosis of unilateral peripheral vestibular dysfunctionTong‐tong Zhao0Meng‐lu Zhang1Yu‐fei Feng2Qian‐qian Wang3Ning Song4Xu Yang5Xiao‐hong Ba6Department of Neurology The First Affiliated Hospital of Jinzhou Medical University Jinzhou ChinaDepartment of Neurology The First Affiliated Hospital of Jinzhou Medical University Jinzhou ChinaDepartment of Neurology The First Affiliated Hospital of Jinzhou Medical University Jinzhou ChinaDepartment of Neurology The First Affiliated Hospital of Jinzhou Medical University Jinzhou ChinaDepartment of Neurology Aerospace Center Hospital, Peking University Aerospace School of Clinical Medicine Beijing ChinaDepartment of Neurology Aerospace Center Hospital, Peking University Aerospace School of Clinical Medicine Beijing ChinaDepartment of Neurology The First Affiliated Hospital of Jinzhou Medical University Jinzhou ChinaAbstract Background Evaluation of vestibular graviceptive pathway (VGP) in patients with unilateral peripheral vestibular dysfunction (UPVD) has received increasing attention from researchers. The study aimed to investigate the value of VGP evaluation in the diagnosis of UPVD. Methods Ninety‐five UPVD patients were divided into attack and remission phase groups. VGP evaluation‐related indicators, including subjective visual vertical (SVV), subjective visual horizontal (SVH), head tilt, ocular torsion (OT), and skew deviation (SD), were measured, and their correlations with cochleovestibular function test results were analyzed. The possible etiologies of contralesional VGP (c‐VGP) were analyzed. Results Positive rates of SVV, SVH, OT, and SD were significantly higher, and the degrees of SVV, SVH, and OT were significantly greater in the attack phase group than the remission phase group. The sides with abnormal VGP evaluation results were correlated with the sides with hearing loss, abnormal caloric, and video head impulse test (vHIT) results. A total of 14 patients showed c‐VGP, and possible etiologies included contralateral benign paroxysmal positional vertigo (n = 4), bilateral hearing loss (n = 8), bilateral vHIT gain reduction (n = 1), autoimmune diseases (n = 6), vascular risk factors (n = 6), lacunar infarction (n = 3), and endolymphatic hydrops (n = 3). Conclusions Alterations in SVV, SVH, OT, and SD were noted in UPVD patients in different phases, which are presumed to be related to dynamic vestibular compensation; correlations between VGP evaluation results and cochleovestibular function test results indicate that VGP evaluation may be helpful for the diagnosis of the side affected in UPVD; the presence of c‐VGP may be related to bilateral labyrinth lesions or endolymphatic hydrops on the affected side; and the involvement of autoimmune mechanisms also deserves attention.https://doi.org/10.1002/brb3.3055ocular tilt reactionsubjective visual horizontalsubjective visual verticalunilateral peripheral vestibular dysfunctionvestibular graviceptive pathway |
| spellingShingle | Tong‐tong Zhao Meng‐lu Zhang Yu‐fei Feng Qian‐qian Wang Ning Song Xu Yang Xiao‐hong Ba The value of vestibular graviceptive pathway evaluation in the diagnosis of unilateral peripheral vestibular dysfunction Brain and Behavior ocular tilt reaction subjective visual horizontal subjective visual vertical unilateral peripheral vestibular dysfunction vestibular graviceptive pathway |
| title | The value of vestibular graviceptive pathway evaluation in the diagnosis of unilateral peripheral vestibular dysfunction |
| title_full | The value of vestibular graviceptive pathway evaluation in the diagnosis of unilateral peripheral vestibular dysfunction |
| title_fullStr | The value of vestibular graviceptive pathway evaluation in the diagnosis of unilateral peripheral vestibular dysfunction |
| title_full_unstemmed | The value of vestibular graviceptive pathway evaluation in the diagnosis of unilateral peripheral vestibular dysfunction |
| title_short | The value of vestibular graviceptive pathway evaluation in the diagnosis of unilateral peripheral vestibular dysfunction |
| title_sort | value of vestibular graviceptive pathway evaluation in the diagnosis of unilateral peripheral vestibular dysfunction |
| topic | ocular tilt reaction subjective visual horizontal subjective visual vertical unilateral peripheral vestibular dysfunction vestibular graviceptive pathway |
| url | https://doi.org/10.1002/brb3.3055 |
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