Investigation of TG-43 dosimetric parameters for 192Ir brachytherapy source using GATE Monte Carlo code

Purpose: According to the revised Task Group number 43 recommendations, a brachytherapy source must be validated against a similar or identical source before its clinical application. The purpose of this investigation is to verify the dosimetric data of the high dose rate (HDR) BEBIG 192Ir source (I...

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Main Authors: Musa Joya, Hassan Ali Nedaie, Ghazale Geraily, Hadi Rezaei, Awaz Bromand, Mahdi Ghorbani, Peyman Sheikhzadeh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Journal of Medical Physics
Subjects:
Online Access:http://www.jmp.org.in/article.asp?issn=0971-6203;year=2023;volume=48;issue=3;spage=268;epage=273;aulast=Joya
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author Musa Joya
Hassan Ali Nedaie
Ghazale Geraily
Hadi Rezaei
Awaz Bromand
Mahdi Ghorbani
Peyman Sheikhzadeh
author_facet Musa Joya
Hassan Ali Nedaie
Ghazale Geraily
Hadi Rezaei
Awaz Bromand
Mahdi Ghorbani
Peyman Sheikhzadeh
author_sort Musa Joya
collection DOAJ
description Purpose: According to the revised Task Group number 43 recommendations, a brachytherapy source must be validated against a similar or identical source before its clinical application. The purpose of this investigation is to verify the dosimetric data of the high dose rate (HDR) BEBIG 192Ir source (Ir2.A85-2). Materials and Methods: The HDR 192Ir encapsulated seed was simulated and its main dosimetric data were calculated using Geant4 Application for Tomographic Emission (GATE) simulation code. Cubic cells were used for the calculation of dose rate constant and radial dose function while for anisotropy function ring cells were used. DoseActors were simulated and attached to the respective cells to obtain the required data. Results: The dose rate constant was obtained as 1.098 ± 0.003 cGy.h − 1.U − 1, differing by 1.0% from the reference value reported by Granero et al. Similarly, the calculated values for radial dose and anisotropy functions presented good agreement with the results obtained by Granero et al. Conclusion: The results of this study suggest that the GATE Monte Carlo code is a valid toolkit for benchmarking brachytherapy sources and can be used for brachytherapy simulation-based studies and verification of brachytherapy treatment planning systems.
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spelling doaj.art-465e13f1688f49f28ebbcccfec12cbdb2023-10-30T10:15:29ZengWolters Kluwer Medknow PublicationsJournal of Medical Physics0971-62031998-39132023-01-0148326827310.4103/jmp.jmp_41_23Investigation of TG-43 dosimetric parameters for 192Ir brachytherapy source using GATE Monte Carlo codeMusa JoyaHassan Ali NedaieGhazale GerailyHadi RezaeiAwaz BromandMahdi GhorbaniPeyman SheikhzadehPurpose: According to the revised Task Group number 43 recommendations, a brachytherapy source must be validated against a similar or identical source before its clinical application. The purpose of this investigation is to verify the dosimetric data of the high dose rate (HDR) BEBIG 192Ir source (Ir2.A85-2). Materials and Methods: The HDR 192Ir encapsulated seed was simulated and its main dosimetric data were calculated using Geant4 Application for Tomographic Emission (GATE) simulation code. Cubic cells were used for the calculation of dose rate constant and radial dose function while for anisotropy function ring cells were used. DoseActors were simulated and attached to the respective cells to obtain the required data. Results: The dose rate constant was obtained as 1.098 ± 0.003 cGy.h − 1.U − 1, differing by 1.0% from the reference value reported by Granero et al. Similarly, the calculated values for radial dose and anisotropy functions presented good agreement with the results obtained by Granero et al. Conclusion: The results of this study suggest that the GATE Monte Carlo code is a valid toolkit for benchmarking brachytherapy sources and can be used for brachytherapy simulation-based studies and verification of brachytherapy treatment planning systems.http://www.jmp.org.in/article.asp?issn=0971-6203;year=2023;volume=48;issue=3;spage=268;epage=273;aulast=Joyabebig 192ir sourcegate codemonte carlo simulationtg-43u1 report
spellingShingle Musa Joya
Hassan Ali Nedaie
Ghazale Geraily
Hadi Rezaei
Awaz Bromand
Mahdi Ghorbani
Peyman Sheikhzadeh
Investigation of TG-43 dosimetric parameters for 192Ir brachytherapy source using GATE Monte Carlo code
Journal of Medical Physics
bebig 192ir source
gate code
monte carlo simulation
tg-43u1 report
title Investigation of TG-43 dosimetric parameters for 192Ir brachytherapy source using GATE Monte Carlo code
title_full Investigation of TG-43 dosimetric parameters for 192Ir brachytherapy source using GATE Monte Carlo code
title_fullStr Investigation of TG-43 dosimetric parameters for 192Ir brachytherapy source using GATE Monte Carlo code
title_full_unstemmed Investigation of TG-43 dosimetric parameters for 192Ir brachytherapy source using GATE Monte Carlo code
title_short Investigation of TG-43 dosimetric parameters for 192Ir brachytherapy source using GATE Monte Carlo code
title_sort investigation of tg 43 dosimetric parameters for 192ir brachytherapy source using gate monte carlo code
topic bebig 192ir source
gate code
monte carlo simulation
tg-43u1 report
url http://www.jmp.org.in/article.asp?issn=0971-6203;year=2023;volume=48;issue=3;spage=268;epage=273;aulast=Joya
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