Copper-catalysed asymmetric annulation of yne-allylic esters with amines to access axially chiral arylpyrroles
Abstract The construction of atropisomers with 1,2-diaxes, while maintaining high enantiocontrol, presents a significant challenge due to the dynamic nature of steric hindrance at ortho-aryl substituents. Although various catalytic asymmetric methods have been developed for accessing axially chiral...
| Główni autorzy: | , , , , , , , , , , |
|---|---|
| Format: | Artykuł |
| Język: | English |
| Wydane: |
Nature Portfolio
2024-08-01
|
| Seria: | Nature Communications |
| Dostęp online: | https://doi.org/10.1038/s41467-024-50896-8 |