Internalization of apoptotic cells during efferocytosis requires Mertk-mediated calcium influx

Abstract Phagocytosis of apoptotic cells, called efferocytosis, requires calcium inside and outside of phagocytes. Due to its necessity, calcium flux is sophisticatedly modulated, and the level of intracellular calcium in phagocytes is ultimately elevated during efferocytosis. However, the role of e...

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Bibliographic Details
Main Authors: Susumin Yang, Chanhyuk Min, Hyunji Moon, Byeongjin Moon, Juyeon Lee, Jaeseon Jeon, Hagyeong Kwon, Deokyun Jang, Daeho Park
Format: Article
Language:English
Published: Nature Publishing Group 2023-06-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05925-7