Lactate exacerbates lung damage induced by nanomicroplastic through the gut microbiota–HIF1a/PTBP1 pathway

Lactate exacerbates lung damage induced by nanomicroplastic through the gut microbiota–HIF1a/PTBP1 pathway

Abstract Exposure to nanomicroplastics (nano-MPs) can induce lung damage. The gut microbiota is a critical modulator of the gut–lung axis. However, the mechanisms underlying these interactions have not been elucidated. This study explored the role of lactate, a key metabolite of the microbiota, in t...

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Bibliographic Details
Main Authors: Lihui Xuan, Zheng Xu, Jinhua Luo, Yin Wang, Yuhui Yan, Can Qu, Zuozhong Xie, Magdalena Skonieczna, Ping-Kun Zhou, Ruixue Huang
Format: Article
Language:English
Published: Nature Publishing Group 2023-12-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-023-01129-3

Internet

https://doi.org/10.1038/s12276-023-01129-3

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