Efficient synthesis of furfurylamine from biomass via a hybrid strategy in an EaCl:Gly–water medium
The objective of this work was to develop an efficient approach for chemoenzymatically transforming biomass to furfurylamine by bridging chemocatalysis and biocatalysis in a deep eutectic solvent of EaCl:Gly–water. Using hydroxyapatite (HAP) as support, heterogeneous catalyst SO42−/SnO2–HAP was synt...
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| Format: | Article |
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Frontiers Media S.A.
2023-03-01
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| Series: | Frontiers in Bioengineering and Biotechnology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2023.1144787/full |
| _version_ | 1797869538463711232 |
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| author | Wei He Yu-Cai He Jianren Ye |
| author_facet | Wei He Yu-Cai He Jianren Ye |
| author_sort | Wei He |
| collection | DOAJ |
| description | The objective of this work was to develop an efficient approach for chemoenzymatically transforming biomass to furfurylamine by bridging chemocatalysis and biocatalysis in a deep eutectic solvent of EaCl:Gly–water. Using hydroxyapatite (HAP) as support, heterogeneous catalyst SO42−/SnO2–HAP was synthesized for transforming lignocellulosic biomass into furfural using organic acid as a co-catalyst. The turnover frequency (TOF) was correlated with the pKa value of the used organic acid. Corncob was transformed by oxalic acid (pKa = 1.25) (0.4 wt%) plus SO42−/SnO2–HAP (2.0 wt%) to produce furfural with a yield of 48.2% and a TOF of 6.33 h-1 in water. In deep eutectic solvent EaCl:Gly–water (1:2, v/v), co-catalysis with SO42−/SnO2–HAP and oxalic acid was utilized to transform corncob, rice straw, reed leaf, and sugarcane bagasse for the production of furfural with the yield of 42.4%–59.3% (based on the xylan content) at 180°C after 10 min. The formed furfural could be efficiently aminated to furfurylamine with E. coli CCZU-XLS160 cells in the presence of NH4Cl (as an amine donor). As a result of the biological amination of furfural derived from corncob, rice straw, reed leaf, and sugarcane bagasse for 24 h, the yields of furfurylamine reached >99%, with a productivity of 0.31–0.43 g furfurylamine per g xylan. In EaCl:Gly–water, an efficient chemoenzymatic catalysis strategy was employed to valorize lignocellulosic biomass into valuable furan chemicals. |
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| issn | 2296-4185 |
| language | English |
| last_indexed | 2024-04-10T00:14:16Z |
| publishDate | 2023-03-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Bioengineering and Biotechnology |
| spelling | doaj.art-46655089e8814c5c923df529cf5862f32023-03-16T06:22:58ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852023-03-011110.3389/fbioe.2023.11447871144787Efficient synthesis of furfurylamine from biomass via a hybrid strategy in an EaCl:Gly–water mediumWei He0Yu-Cai He1Jianren Ye2College of Biology and the Environment, Nanjing Forestry University, Nanjing, ChinaSchool of Pharmacy, Changzhou University, Changzhou, ChinaCollege of Forestry, Nanjing Forestry University, Nanjing, ChinaThe objective of this work was to develop an efficient approach for chemoenzymatically transforming biomass to furfurylamine by bridging chemocatalysis and biocatalysis in a deep eutectic solvent of EaCl:Gly–water. Using hydroxyapatite (HAP) as support, heterogeneous catalyst SO42−/SnO2–HAP was synthesized for transforming lignocellulosic biomass into furfural using organic acid as a co-catalyst. The turnover frequency (TOF) was correlated with the pKa value of the used organic acid. Corncob was transformed by oxalic acid (pKa = 1.25) (0.4 wt%) plus SO42−/SnO2–HAP (2.0 wt%) to produce furfural with a yield of 48.2% and a TOF of 6.33 h-1 in water. In deep eutectic solvent EaCl:Gly–water (1:2, v/v), co-catalysis with SO42−/SnO2–HAP and oxalic acid was utilized to transform corncob, rice straw, reed leaf, and sugarcane bagasse for the production of furfural with the yield of 42.4%–59.3% (based on the xylan content) at 180°C after 10 min. The formed furfural could be efficiently aminated to furfurylamine with E. coli CCZU-XLS160 cells in the presence of NH4Cl (as an amine donor). As a result of the biological amination of furfural derived from corncob, rice straw, reed leaf, and sugarcane bagasse for 24 h, the yields of furfurylamine reached >99%, with a productivity of 0.31–0.43 g furfurylamine per g xylan. In EaCl:Gly–water, an efficient chemoenzymatic catalysis strategy was employed to valorize lignocellulosic biomass into valuable furan chemicals.https://www.frontiersin.org/articles/10.3389/fbioe.2023.1144787/fulllignocellulosefurfuralfurfurylamineSO42−/SnO2–HAPdeep eutectic solvent |
| spellingShingle | Wei He Yu-Cai He Jianren Ye Efficient synthesis of furfurylamine from biomass via a hybrid strategy in an EaCl:Gly–water medium Frontiers in Bioengineering and Biotechnology lignocellulose furfural furfurylamine SO42−/SnO2–HAP deep eutectic solvent |
| title | Efficient synthesis of furfurylamine from biomass via a hybrid strategy in an EaCl:Gly–water medium |
| title_full | Efficient synthesis of furfurylamine from biomass via a hybrid strategy in an EaCl:Gly–water medium |
| title_fullStr | Efficient synthesis of furfurylamine from biomass via a hybrid strategy in an EaCl:Gly–water medium |
| title_full_unstemmed | Efficient synthesis of furfurylamine from biomass via a hybrid strategy in an EaCl:Gly–water medium |
| title_short | Efficient synthesis of furfurylamine from biomass via a hybrid strategy in an EaCl:Gly–water medium |
| title_sort | efficient synthesis of furfurylamine from biomass via a hybrid strategy in an eacl gly water medium |
| topic | lignocellulose furfural furfurylamine SO42−/SnO2–HAP deep eutectic solvent |
| url | https://www.frontiersin.org/articles/10.3389/fbioe.2023.1144787/full |
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