Evaluating the effect of therapeutic stem cells on TRAIL resistant and sensitive medulloblastomas.
Mesenchymal stem cells (MSC) are emerging as novel cell-based delivery agents; however, a thorough investigation addressing their therapeutic potential in medulloblastomas (MB) has not been explored to date. In this study, we engineered human MSC to express a potent and secretable variant of a tumor...
Main Authors: | Irina Nesterenko, Simone Wanningen, Tugba Bagci-Onder, Maarten Anderegg, Khalid Shah |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3492275?pdf=render |
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