Urinary Aspergillosis in a Patient with Systemic Lupus Erythematosus (SLE)

Aspergillosis is an opportunistic mycosis that generally affects the lungs. The fungus was cleared by the immune system of a healthy host. Extrapulmonary forms are very rare, and there are few reports of urinary aspergillosis. In this case report, we describe a 62-year-old woman with systemic lupus...

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Main Authors: Mayara Gabriele Toledo, Hugo Rodrigues Alves, Isadora Cambruzzi, Laís Lopes Pires, Mariana Rossi, Ana Carolina Gonçalves Brito, Andrea D’Avila Freitas, Natalia Chilinque Zambão da Silva
Format: Article
Language:English
Published: Hindawi Limited 2023-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2023/5575300
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author Mayara Gabriele Toledo
Hugo Rodrigues Alves
Isadora Cambruzzi
Laís Lopes Pires
Mariana Rossi
Ana Carolina Gonçalves Brito
Andrea D’Avila Freitas
Natalia Chilinque Zambão da Silva
author_facet Mayara Gabriele Toledo
Hugo Rodrigues Alves
Isadora Cambruzzi
Laís Lopes Pires
Mariana Rossi
Ana Carolina Gonçalves Brito
Andrea D’Avila Freitas
Natalia Chilinque Zambão da Silva
author_sort Mayara Gabriele Toledo
collection DOAJ
description Aspergillosis is an opportunistic mycosis that generally affects the lungs. The fungus was cleared by the immune system of a healthy host. Extrapulmonary forms are very rare, and there are few reports of urinary aspergillosis. In this case report, we describe a 62-year-old woman with systemic lupus erythematosus (SLE) with complaints of fever and dysuria. The patient had recurrent episodes of urinary tract infection and several hospitalizations. A computed tomography revealed an amorphous mass in the left kidney and bladder. After partial resection of the material was referred for analysis, Aspergillus infection was suspected and confirmed by culture. Successful treatment with voriconazole was provided. Diagnosis of localized primary renal Aspergillus infection in a patient with SLE requires careful investigation due to its benign presentation and lack of associated systemic clinical features.
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spelling doaj.art-46697601630f4ae9a5697023227a19652023-05-12T08:16:08ZengHindawi LimitedCase Reports in Infectious Diseases2090-66332023-01-01202310.1155/2023/5575300Urinary Aspergillosis in a Patient with Systemic Lupus Erythematosus (SLE)Mayara Gabriele Toledo0Hugo Rodrigues Alves1Isadora Cambruzzi2Laís Lopes Pires3Mariana Rossi4Ana Carolina Gonçalves Brito5Andrea D’Avila Freitas6Natalia Chilinque Zambão da Silva7Fluminense Federal UniversityFluminense Federal UniversityNiterói Hospital ComplexNiterói Hospital ComplexNiterói Hospital ComplexPathologist at Diagnostics of America (DASA)Infectologist at Niterói Hospital ComplexDepartment of Clinical MedicineAspergillosis is an opportunistic mycosis that generally affects the lungs. The fungus was cleared by the immune system of a healthy host. Extrapulmonary forms are very rare, and there are few reports of urinary aspergillosis. In this case report, we describe a 62-year-old woman with systemic lupus erythematosus (SLE) with complaints of fever and dysuria. The patient had recurrent episodes of urinary tract infection and several hospitalizations. A computed tomography revealed an amorphous mass in the left kidney and bladder. After partial resection of the material was referred for analysis, Aspergillus infection was suspected and confirmed by culture. Successful treatment with voriconazole was provided. Diagnosis of localized primary renal Aspergillus infection in a patient with SLE requires careful investigation due to its benign presentation and lack of associated systemic clinical features.http://dx.doi.org/10.1155/2023/5575300
spellingShingle Mayara Gabriele Toledo
Hugo Rodrigues Alves
Isadora Cambruzzi
Laís Lopes Pires
Mariana Rossi
Ana Carolina Gonçalves Brito
Andrea D’Avila Freitas
Natalia Chilinque Zambão da Silva
Urinary Aspergillosis in a Patient with Systemic Lupus Erythematosus (SLE)
Case Reports in Infectious Diseases
title Urinary Aspergillosis in a Patient with Systemic Lupus Erythematosus (SLE)
title_full Urinary Aspergillosis in a Patient with Systemic Lupus Erythematosus (SLE)
title_fullStr Urinary Aspergillosis in a Patient with Systemic Lupus Erythematosus (SLE)
title_full_unstemmed Urinary Aspergillosis in a Patient with Systemic Lupus Erythematosus (SLE)
title_short Urinary Aspergillosis in a Patient with Systemic Lupus Erythematosus (SLE)
title_sort urinary aspergillosis in a patient with systemic lupus erythematosus sle
url http://dx.doi.org/10.1155/2023/5575300
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