Three-Year Follow-Up Detecting Choroidal Neovascularization with Swept Source Optical Coherence Tomography Angiography (SS-OCTA) after Successful Half-Fluence Photodynamic Therapy for Chronic Central Serous Chorioretinopathy
<b>Purpose</b>: To assess the clinical course, structural changes, and choroidal neovascularization detection by SS-OCTA in long-standing and resolved patients with chronic central serous chorioretinopathy (cCSC) after successful half-fluence photodynamic therapy (hf-PDT) treatment. <...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-08-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/13/17/2792 |
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| author | Olivia Esteban-Floría Guillermo Pérez-Rivasés Ana Honrubia-Grijalbo Isabel Bartolomé-Sesé María Dolores Díaz-Barreda Ana Boned-Murillo Pablo Cisneros-Arias Javier Mateo-Gabás Francisco-Javier Ascaso-Puyelo |
| author_facet | Olivia Esteban-Floría Guillermo Pérez-Rivasés Ana Honrubia-Grijalbo Isabel Bartolomé-Sesé María Dolores Díaz-Barreda Ana Boned-Murillo Pablo Cisneros-Arias Javier Mateo-Gabás Francisco-Javier Ascaso-Puyelo |
| author_sort | Olivia Esteban-Floría |
| collection | DOAJ |
| description | <b>Purpose</b>: To assess the clinical course, structural changes, and choroidal neovascularization detection by SS-OCTA in long-standing and resolved patients with chronic central serous chorioretinopathy (cCSC) after successful half-fluence photodynamic therapy (hf-PDT) treatment. <b>Methods:</b> Twenty-four eyes presenting with cCSC were examined with SS-OCTA and were classified as choroidal neovascular (CNV) or non-choroidal neovascular (non-CNV) cCSC depending on the vascular pattern detected by SS-OCTA after one, two, and three years after hf-PDT. Two groups were compared based on the following clinical findings: demographic characteristics, time of clinical signs, best corrected visual acuity (BCVA), central retinal thickness (CRT), central choroidal thickness (CFT), subretinal fluid (SRF), flat, irregular pigment epithelial detachment (FIPED), and features of fluorescein angiography (FA) and vascular pattern by SS-OCTA. <b>Results:</b> All patients showed resolved cCSC during follow-up after hf-PDT. A total of 5 of 24 (20.8%) eyes showed a neovascular pattern by SS-OCTA. No differences between BCVA, CRT, SRF, FIPED, or FA features were found between both groups (<i>p</i> > 0.05). However, CFT and older age were associated with a neovascular pattern by SS-OCTA (<i>p</i> < 0.05) in follow-up. No signs of neovascular activity were detected by SS-OCT during follow-up in CNV cCSC patients, and no antiVEGF treatment was required for three-year follow-ups. <b>Conclusions:</b> Despite patients with cCSC showing a favorable clinical response after hf-PDT, lower foveal thickness and older age were associated with CNV patterns by SS-OCTA during follow-up. |
| first_indexed | 2024-03-10T23:25:36Z |
| format | Article |
| id | doaj.art-466a98e80995489a860f869b29c7de81 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-10T23:25:36Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-466a98e80995489a860f869b29c7de812023-11-19T07:59:39ZengMDPI AGDiagnostics2075-44182023-08-011317279210.3390/diagnostics13172792Three-Year Follow-Up Detecting Choroidal Neovascularization with Swept Source Optical Coherence Tomography Angiography (SS-OCTA) after Successful Half-Fluence Photodynamic Therapy for Chronic Central Serous ChorioretinopathyOlivia Esteban-Floría0Guillermo Pérez-Rivasés1Ana Honrubia-Grijalbo2Isabel Bartolomé-Sesé3María Dolores Díaz-Barreda4Ana Boned-Murillo5Pablo Cisneros-Arias6Javier Mateo-Gabás7Francisco-Javier Ascaso-Puyelo8Department of Ophthalmology, Hospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, SpainDepartment of Ophthalmology, Hospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, SpainDepartment of Ophthalmology, Hospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, SpainDepartment of Ophthalmology, Hospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, SpainDepartment of Ophthalmology, Hospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, SpainDepartment of Ophthalmology, Hospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, SpainDepartment of Ophthalmology, Hospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, SpainDepartment of Ophthalmology, Hospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, SpainDepartment of Ophthalmology, Hospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, Spain<b>Purpose</b>: To assess the clinical course, structural changes, and choroidal neovascularization detection by SS-OCTA in long-standing and resolved patients with chronic central serous chorioretinopathy (cCSC) after successful half-fluence photodynamic therapy (hf-PDT) treatment. <b>Methods:</b> Twenty-four eyes presenting with cCSC were examined with SS-OCTA and were classified as choroidal neovascular (CNV) or non-choroidal neovascular (non-CNV) cCSC depending on the vascular pattern detected by SS-OCTA after one, two, and three years after hf-PDT. Two groups were compared based on the following clinical findings: demographic characteristics, time of clinical signs, best corrected visual acuity (BCVA), central retinal thickness (CRT), central choroidal thickness (CFT), subretinal fluid (SRF), flat, irregular pigment epithelial detachment (FIPED), and features of fluorescein angiography (FA) and vascular pattern by SS-OCTA. <b>Results:</b> All patients showed resolved cCSC during follow-up after hf-PDT. A total of 5 of 24 (20.8%) eyes showed a neovascular pattern by SS-OCTA. No differences between BCVA, CRT, SRF, FIPED, or FA features were found between both groups (<i>p</i> > 0.05). However, CFT and older age were associated with a neovascular pattern by SS-OCTA (<i>p</i> < 0.05) in follow-up. No signs of neovascular activity were detected by SS-OCT during follow-up in CNV cCSC patients, and no antiVEGF treatment was required for three-year follow-ups. <b>Conclusions:</b> Despite patients with cCSC showing a favorable clinical response after hf-PDT, lower foveal thickness and older age were associated with CNV patterns by SS-OCTA during follow-up.https://www.mdpi.com/2075-4418/13/17/2792swept-source optical coherence tomography angiography (SS-OCTA)neovascular chronic central serous chorioretinopathyphotodynamic therapy |
| spellingShingle | Olivia Esteban-Floría Guillermo Pérez-Rivasés Ana Honrubia-Grijalbo Isabel Bartolomé-Sesé María Dolores Díaz-Barreda Ana Boned-Murillo Pablo Cisneros-Arias Javier Mateo-Gabás Francisco-Javier Ascaso-Puyelo Three-Year Follow-Up Detecting Choroidal Neovascularization with Swept Source Optical Coherence Tomography Angiography (SS-OCTA) after Successful Half-Fluence Photodynamic Therapy for Chronic Central Serous Chorioretinopathy Diagnostics swept-source optical coherence tomography angiography (SS-OCTA) neovascular chronic central serous chorioretinopathy photodynamic therapy |
| title | Three-Year Follow-Up Detecting Choroidal Neovascularization with Swept Source Optical Coherence Tomography Angiography (SS-OCTA) after Successful Half-Fluence Photodynamic Therapy for Chronic Central Serous Chorioretinopathy |
| title_full | Three-Year Follow-Up Detecting Choroidal Neovascularization with Swept Source Optical Coherence Tomography Angiography (SS-OCTA) after Successful Half-Fluence Photodynamic Therapy for Chronic Central Serous Chorioretinopathy |
| title_fullStr | Three-Year Follow-Up Detecting Choroidal Neovascularization with Swept Source Optical Coherence Tomography Angiography (SS-OCTA) after Successful Half-Fluence Photodynamic Therapy for Chronic Central Serous Chorioretinopathy |
| title_full_unstemmed | Three-Year Follow-Up Detecting Choroidal Neovascularization with Swept Source Optical Coherence Tomography Angiography (SS-OCTA) after Successful Half-Fluence Photodynamic Therapy for Chronic Central Serous Chorioretinopathy |
| title_short | Three-Year Follow-Up Detecting Choroidal Neovascularization with Swept Source Optical Coherence Tomography Angiography (SS-OCTA) after Successful Half-Fluence Photodynamic Therapy for Chronic Central Serous Chorioretinopathy |
| title_sort | three year follow up detecting choroidal neovascularization with swept source optical coherence tomography angiography ss octa after successful half fluence photodynamic therapy for chronic central serous chorioretinopathy |
| topic | swept-source optical coherence tomography angiography (SS-OCTA) neovascular chronic central serous chorioretinopathy photodynamic therapy |
| url | https://www.mdpi.com/2075-4418/13/17/2792 |
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