The experience of use of everolimus in patients having undergone to orthotopic liver transplantation
The efficacy and safety of everolimus in 10 recipients of liver in the post-transplant period with simultaneous reducing the dose of calcineurin inhibitors are analyzed. After conversion of immunosuppression the duration of monitoring of patients ranged from 4 to 18 months. Episodes of acute cellula...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department
2018-08-01
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| Series: | Трансплантология (Москва) |
| Subjects: | |
| Online Access: | https://www.jtransplantologiya.ru/jour/article/view/373 |
| _version_ | 1797702964249362432 |
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| author | V. E. Syutkin O. I. Andreytseva V. P. Nikulina A. O. Chugunov |
| author_facet | V. E. Syutkin O. I. Andreytseva V. P. Nikulina A. O. Chugunov |
| author_sort | V. E. Syutkin |
| collection | DOAJ |
| description | The efficacy and safety of everolimus in 10 recipients of liver in the post-transplant period with simultaneous reducing the dose of calcineurin inhibitors are analyzed. After conversion of immunosuppression the duration of monitoring of patients ranged from 4 to 18 months. Episodes of acute cellular rejection were not observed. Already in the first month after inclusion of everolimus in the scheme of immunosuppressive therapy, there was observed an improvement in renal function, which persisted at follow-up of patients. No serious adverse events were observed. |
| first_indexed | 2024-03-12T04:57:34Z |
| format | Article |
| id | doaj.art-466d7fab492647a7bbd596a22b0d411e |
| institution | Directory Open Access Journal |
| issn | 2074-0506 2542-0909 |
| language | English |
| last_indexed | 2024-03-12T04:57:34Z |
| publishDate | 2018-08-01 |
| publisher | N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department |
| record_format | Article |
| series | Трансплантология (Москва) |
| spelling | doaj.art-466d7fab492647a7bbd596a22b0d411e2023-09-03T09:14:38ZengN.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare DepartmentТрансплантология (Москва)2074-05062542-09092018-08-0101-2101410.23873/2074-0506-2012-0-1-2-10-14360The experience of use of everolimus in patients having undergone to orthotopic liver transplantationV. E. Syutkin0O. I. Andreytseva1V. P. Nikulina2A. O. Chugunov3НИИ СП им. Н.В. СклифосовскогоНИИ СП им. Н.В. СклифосовскогоНИИ СП им. Н.В. СклифосовскогоНИИ СП им. Н.В. СклифосовскогоThe efficacy and safety of everolimus in 10 recipients of liver in the post-transplant period with simultaneous reducing the dose of calcineurin inhibitors are analyzed. After conversion of immunosuppression the duration of monitoring of patients ranged from 4 to 18 months. Episodes of acute cellular rejection were not observed. Already in the first month after inclusion of everolimus in the scheme of immunosuppressive therapy, there was observed an improvement in renal function, which persisted at follow-up of patients. No serious adverse events were observed.https://www.jtransplantologiya.ru/jour/article/view/373эверолимустрансплантация печениингибиторы кальциневринапочечная недостаточность |
| spellingShingle | V. E. Syutkin O. I. Andreytseva V. P. Nikulina A. O. Chugunov The experience of use of everolimus in patients having undergone to orthotopic liver transplantation Трансплантология (Москва) эверолимус трансплантация печени ингибиторы кальциневрина почечная недостаточность |
| title | The experience of use of everolimus in patients having undergone to orthotopic liver transplantation |
| title_full | The experience of use of everolimus in patients having undergone to orthotopic liver transplantation |
| title_fullStr | The experience of use of everolimus in patients having undergone to orthotopic liver transplantation |
| title_full_unstemmed | The experience of use of everolimus in patients having undergone to orthotopic liver transplantation |
| title_short | The experience of use of everolimus in patients having undergone to orthotopic liver transplantation |
| title_sort | experience of use of everolimus in patients having undergone to orthotopic liver transplantation |
| topic | эверолимус трансплантация печени ингибиторы кальциневрина почечная недостаточность |
| url | https://www.jtransplantologiya.ru/jour/article/view/373 |
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