HAp/β-TCP Biphasic Ceramics Obtained by the Pechini Method: An Antibacterial Approach
Calcium phosphates (CaPs) have broad applications in biomedicine, with the most used phases being hydroxyapatite (HAp) and β-tricalcium phosphate (β-TCP) due to their similarity with natural bone. There are several methods for obtaining CaPs. However, the Pechini method attracts much attention due t...
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MDPI AG
2022-11-01
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| Series: | Minerals |
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| author | Geysivana K. Carvalho José R. S. Farias Idglan S. Lima Ariane M. Nascimento Gelmires A. Neves Romualdo Menezes Josy A. Osajima Aluska Braga Edson C. Silva-Filho |
| author_facet | Geysivana K. Carvalho José R. S. Farias Idglan S. Lima Ariane M. Nascimento Gelmires A. Neves Romualdo Menezes Josy A. Osajima Aluska Braga Edson C. Silva-Filho |
| author_sort | Geysivana K. Carvalho |
| collection | DOAJ |
| description | Calcium phosphates (CaPs) have broad applications in biomedicine, with the most used phases being hydroxyapatite (HAp) and β-tricalcium phosphate (β-TCP) due to their similarity with natural bone. There are several methods for obtaining CaPs. However, the Pechini method attracts much attention due to its advantages: homogeneous molecular mixing, obtaining nanocrystalline particles, low processing temperature, generating nanometric particles, and simplicity. However, this method is little discussed for the synthesis of CaPs. This work aimed to synthesize CaPs using the Pechini method, analyzing the antibacterial properties. The samples were characterized by X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), thermogravimetric analysis (TG/DTG), scanning electron microscopy (SEM), and energy dispersive spectroscopy (EDS). The XRD confirmed obtaining the biphasic ceramic of HAp, with no other phase as an impurity, where the ratio between citric acid and ethylene glycol (AC/EG) influenced the percentage of HAp phases and β-TCP formed. Thermogravimetric analysis showed a mass loss of approximately 7%. SEM observed the formation of post-agglomerates and irregular shapes. The bacteriological test was satisfactory. The samples showed above 25% inhibition for the growth of <i>Staphylococcus aureus</i> and <i>Escherichia coli</i> bacteria. |
| first_indexed | 2024-03-09T16:04:06Z |
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| id | doaj.art-466f58cd9dca450bbbdf27a3ee08ee03 |
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| issn | 2075-163X |
| language | English |
| last_indexed | 2024-03-09T16:04:06Z |
| publishDate | 2022-11-01 |
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| record_format | Article |
| series | Minerals |
| spelling | doaj.art-466f58cd9dca450bbbdf27a3ee08ee032023-11-24T16:50:32ZengMDPI AGMinerals2075-163X2022-11-011212148210.3390/min12121482HAp/β-TCP Biphasic Ceramics Obtained by the Pechini Method: An Antibacterial ApproachGeysivana K. Carvalho0José R. S. Farias1Idglan S. Lima2Ariane M. Nascimento3Gelmires A. Neves4Romualdo Menezes5Josy A. Osajima6Aluska Braga7Edson C. Silva-Filho8Interdisciplinary Laboratory of Advanced Materials, Federal University of Piauí, Teresina 64064-260, BrazilDevelopment Laboratory of Ceramic materials (LaDeC), Federal University of Piauí, Teresina 64049-550, BrazilInterdisciplinary Laboratory of Advanced Materials, Federal University of Piauí, Teresina 64064-260, BrazilInterdisciplinary Laboratory of Advanced Materials, Federal University of Piauí, Teresina 64064-260, BrazilAcademic Unit of Materials Engineering, Federal University of Campina Grande, Campina Grande 58429-900, BrazilAcademic Unit of Materials Engineering, Federal University of Campina Grande, Campina Grande 58429-900, BrazilInterdisciplinary Laboratory of Advanced Materials, Federal University of Piauí, Teresina 64064-260, BrazilDevelopment Laboratory of Ceramic materials (LaDeC), Federal University of Piauí, Teresina 64049-550, BrazilInterdisciplinary Laboratory of Advanced Materials, Federal University of Piauí, Teresina 64064-260, BrazilCalcium phosphates (CaPs) have broad applications in biomedicine, with the most used phases being hydroxyapatite (HAp) and β-tricalcium phosphate (β-TCP) due to their similarity with natural bone. There are several methods for obtaining CaPs. However, the Pechini method attracts much attention due to its advantages: homogeneous molecular mixing, obtaining nanocrystalline particles, low processing temperature, generating nanometric particles, and simplicity. However, this method is little discussed for the synthesis of CaPs. This work aimed to synthesize CaPs using the Pechini method, analyzing the antibacterial properties. The samples were characterized by X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), thermogravimetric analysis (TG/DTG), scanning electron microscopy (SEM), and energy dispersive spectroscopy (EDS). The XRD confirmed obtaining the biphasic ceramic of HAp, with no other phase as an impurity, where the ratio between citric acid and ethylene glycol (AC/EG) influenced the percentage of HAp phases and β-TCP formed. Thermogravimetric analysis showed a mass loss of approximately 7%. SEM observed the formation of post-agglomerates and irregular shapes. The bacteriological test was satisfactory. The samples showed above 25% inhibition for the growth of <i>Staphylococcus aureus</i> and <i>Escherichia coli</i> bacteria.https://www.mdpi.com/2075-163X/12/12/1482calcium phosphateantimicrobialcharacterization |
| spellingShingle | Geysivana K. Carvalho José R. S. Farias Idglan S. Lima Ariane M. Nascimento Gelmires A. Neves Romualdo Menezes Josy A. Osajima Aluska Braga Edson C. Silva-Filho HAp/β-TCP Biphasic Ceramics Obtained by the Pechini Method: An Antibacterial Approach Minerals calcium phosphate antimicrobial characterization |
| title | HAp/β-TCP Biphasic Ceramics Obtained by the Pechini Method: An Antibacterial Approach |
| title_full | HAp/β-TCP Biphasic Ceramics Obtained by the Pechini Method: An Antibacterial Approach |
| title_fullStr | HAp/β-TCP Biphasic Ceramics Obtained by the Pechini Method: An Antibacterial Approach |
| title_full_unstemmed | HAp/β-TCP Biphasic Ceramics Obtained by the Pechini Method: An Antibacterial Approach |
| title_short | HAp/β-TCP Biphasic Ceramics Obtained by the Pechini Method: An Antibacterial Approach |
| title_sort | hap β tcp biphasic ceramics obtained by the pechini method an antibacterial approach |
| topic | calcium phosphate antimicrobial characterization |
| url | https://www.mdpi.com/2075-163X/12/12/1482 |
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