Childhood diarrhoeal deaths in seven low- and middle-income countries
Objective To investigate the clinical characteristics of children who died from diarrhoea in low- and middle-income countries, such as the duration of diarrhoea, comorbid conditions, care-seeking behaviour and oral rehydration therapy use. Methods The study included verbal autopsy data on children...
| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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The World Health Organization
2014-09-01
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| Series: | Bulletin of the World Health Organization |
| Online Access: | http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0042-96862014000900011&lng=en&tlng=en |
| _version_ | 1797288360661745664 |
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| author | Ahmed Ehsanur Rahman Md Moinuddin Mitike Molla Alemayehu Worku Lisa Hurt Betty Kirkwood Sanjana Brahmawar Mohan Sarmila Mazumder Zulfiqar Bhutta Farrukh Raza Sigilbert Mrema Honorati Masanja Daniel Kadobera Peter Waiswa Rajiv Bahl Mike Zangenberg Lulu Muhe |
| author_facet | Ahmed Ehsanur Rahman Md Moinuddin Mitike Molla Alemayehu Worku Lisa Hurt Betty Kirkwood Sanjana Brahmawar Mohan Sarmila Mazumder Zulfiqar Bhutta Farrukh Raza Sigilbert Mrema Honorati Masanja Daniel Kadobera Peter Waiswa Rajiv Bahl Mike Zangenberg Lulu Muhe |
| author_sort | Ahmed Ehsanur Rahman |
| collection | DOAJ |
| description | Objective To investigate the clinical characteristics of children who died from diarrhoea in low- and middle-income countries, such as the duration of diarrhoea, comorbid conditions, care-seeking behaviour and oral rehydration therapy use. Methods The study included verbal autopsy data on children who died from diarrhoea between 2000 and 2012 at seven sites in Bangladesh, Ethiopia, Ghana, India, Pakistan, Uganda and the United Republic of Tanzania, respectively. Data came from demographic surveillance sites, randomized trials and an extended Demographic and Health Survey. The type of diarrhoea was classified as acute watery, acute bloody or persistent and risk factors were identified. Deaths in children aged 1 to 11 months and 1 to 4 years were analysed separately. Findings The proportion of childhood deaths due to diarrhoea varied considerably across the seven sites from less than 3% to 30%. Among children aged 1–4 years, acute watery diarrhoea accounted for 31–69% of diarrhoeal deaths, acute bloody diarrhoea for 12–28%, and persistent diarrhoea for 12–56%. Among infants aged 1–11 months, persistent diarrhoea accounted for over 30% of diarrhoeal deaths in Ethiopia, India, Pakistan, Uganda and the United Republic of Tanzania. At most sites, more than 40% of children who died from persistent diarrhoea were malnourished. Conclusion Persistent diarrhoea remains an important cause of diarrhoeal death in young children in low- and middle-income countries. Research is needed on the public health burden of persistent diarrhoea and current treatment practices to understand why children are still dying from the condition. |
| first_indexed | 2024-03-07T18:48:14Z |
| format | Article |
| id | doaj.art-4670fa5424d44323ba5e5ed6e435f37d |
| institution | Directory Open Access Journal |
| issn | 0042-9686 |
| language | English |
| last_indexed | 2024-03-07T18:48:14Z |
| publishDate | 2014-09-01 |
| publisher | The World Health Organization |
| record_format | Article |
| series | Bulletin of the World Health Organization |
| spelling | doaj.art-4670fa5424d44323ba5e5ed6e435f37d2024-03-02T02:11:14ZengThe World Health OrganizationBulletin of the World Health Organization0042-96862014-09-0192966467110.2471/BLT.13.134809S0042-96862014000900011Childhood diarrhoeal deaths in seven low- and middle-income countriesAhmed Ehsanur RahmanMd MoinuddinMitike MollaAlemayehu WorkuLisa HurtBetty KirkwoodSanjana Brahmawar MohanSarmila MazumderZulfiqar BhuttaFarrukh RazaSigilbert MremaHonorati MasanjaDaniel KadoberaPeter WaiswaRajiv BahlMike ZangenbergLulu MuheObjective To investigate the clinical characteristics of children who died from diarrhoea in low- and middle-income countries, such as the duration of diarrhoea, comorbid conditions, care-seeking behaviour and oral rehydration therapy use. Methods The study included verbal autopsy data on children who died from diarrhoea between 2000 and 2012 at seven sites in Bangladesh, Ethiopia, Ghana, India, Pakistan, Uganda and the United Republic of Tanzania, respectively. Data came from demographic surveillance sites, randomized trials and an extended Demographic and Health Survey. The type of diarrhoea was classified as acute watery, acute bloody or persistent and risk factors were identified. Deaths in children aged 1 to 11 months and 1 to 4 years were analysed separately. Findings The proportion of childhood deaths due to diarrhoea varied considerably across the seven sites from less than 3% to 30%. Among children aged 1–4 years, acute watery diarrhoea accounted for 31–69% of diarrhoeal deaths, acute bloody diarrhoea for 12–28%, and persistent diarrhoea for 12–56%. Among infants aged 1–11 months, persistent diarrhoea accounted for over 30% of diarrhoeal deaths in Ethiopia, India, Pakistan, Uganda and the United Republic of Tanzania. At most sites, more than 40% of children who died from persistent diarrhoea were malnourished. Conclusion Persistent diarrhoea remains an important cause of diarrhoeal death in young children in low- and middle-income countries. Research is needed on the public health burden of persistent diarrhoea and current treatment practices to understand why children are still dying from the condition.http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0042-96862014000900011&lng=en&tlng=en |
| spellingShingle | Ahmed Ehsanur Rahman Md Moinuddin Mitike Molla Alemayehu Worku Lisa Hurt Betty Kirkwood Sanjana Brahmawar Mohan Sarmila Mazumder Zulfiqar Bhutta Farrukh Raza Sigilbert Mrema Honorati Masanja Daniel Kadobera Peter Waiswa Rajiv Bahl Mike Zangenberg Lulu Muhe Childhood diarrhoeal deaths in seven low- and middle-income countries Bulletin of the World Health Organization |
| title | Childhood diarrhoeal deaths in seven low- and middle-income countries |
| title_full | Childhood diarrhoeal deaths in seven low- and middle-income countries |
| title_fullStr | Childhood diarrhoeal deaths in seven low- and middle-income countries |
| title_full_unstemmed | Childhood diarrhoeal deaths in seven low- and middle-income countries |
| title_short | Childhood diarrhoeal deaths in seven low- and middle-income countries |
| title_sort | childhood diarrhoeal deaths in seven low and middle income countries |
| url | http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0042-96862014000900011&lng=en&tlng=en |
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