Seroprevalence of hepatitis B virus co-infection among HIV-1-positive patients in North-Central Nigeria: The urgent need for surveillance

We report the seroprevalence of hepatitis B surface antigen among HIV-positive patients at a clinic in North-Central Nigeria. Screening for hepatitis B virus was based on serological markers. Alanine aminotransferase levels and CD4+ T-lymphocyte counts were compared between patients. The study showe...

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Main Authors: Terver M. Akindigh, Abba O. Joseph, Chrisitiana O. Robert, Ocheme J. Okojokwu, Juliet N. Okechalu, Aje J. Anejo-Okopi
Format: Article
Language:English
Published: AOSIS 2019-06-01
Series:African Journal of Laboratory Medicine
Subjects:
Online Access:https://ajlmonline.org/index.php/ajlm/article/view/622
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author Terver M. Akindigh
Abba O. Joseph
Chrisitiana O. Robert
Ocheme J. Okojokwu
Juliet N. Okechalu
Aje J. Anejo-Okopi
author_facet Terver M. Akindigh
Abba O. Joseph
Chrisitiana O. Robert
Ocheme J. Okojokwu
Juliet N. Okechalu
Aje J. Anejo-Okopi
author_sort Terver M. Akindigh
collection DOAJ
description We report the seroprevalence of hepatitis B surface antigen among HIV-positive patients at a clinic in North-Central Nigeria. Screening for hepatitis B virus was based on serological markers. Alanine aminotransferase levels and CD4+ T-lymphocyte counts were compared between patients. The study showed that 9.2% were positive for hepatitis B surface antigen with significant differences between alanine aminotransferase levels of patients with and without hepatitis B virus. We recommend a national surveillance system to monitor control efforts.
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spelling doaj.art-46717d9ef1fe4d7d9b1dbfc25dde99872022-12-22T02:10:57ZengAOSISAfrican Journal of Laboratory Medicine2225-20022225-20102019-06-0181e1e410.4102/ajlm.v8i1.622226Seroprevalence of hepatitis B virus co-infection among HIV-1-positive patients in North-Central Nigeria: The urgent need for surveillanceTerver M. Akindigh0Abba O. Joseph1Chrisitiana O. Robert2Ocheme J. Okojokwu3Juliet N. Okechalu4Aje J. Anejo-Okopi5Infectious Diseases Unit, Jos University Teaching Hospital, JosInfectious Diseases Unit, Jos University Teaching Hospital, JosDepartment of Microbiology, Faculty of Natural Sciences, University of Jos, JosDepartment of Microbiology, Faculty of Natural Sciences, University of Jos, JosDepartment of Microbiology, Faculty of Natural Sciences, University of Jos, JosDepartment of Microbiology, Faculty of Natural Sciences, University of Jos, JosWe report the seroprevalence of hepatitis B surface antigen among HIV-positive patients at a clinic in North-Central Nigeria. Screening for hepatitis B virus was based on serological markers. Alanine aminotransferase levels and CD4+ T-lymphocyte counts were compared between patients. The study showed that 9.2% were positive for hepatitis B surface antigen with significant differences between alanine aminotransferase levels of patients with and without hepatitis B virus. We recommend a national surveillance system to monitor control efforts.https://ajlmonline.org/index.php/ajlm/article/view/622Antiretroviral therapyAlanine aminotransferaseCD4+ T-lymphocyteshepatitis B virusHIVSerological markers
spellingShingle Terver M. Akindigh
Abba O. Joseph
Chrisitiana O. Robert
Ocheme J. Okojokwu
Juliet N. Okechalu
Aje J. Anejo-Okopi
Seroprevalence of hepatitis B virus co-infection among HIV-1-positive patients in North-Central Nigeria: The urgent need for surveillance
African Journal of Laboratory Medicine
Antiretroviral therapy
Alanine aminotransferase
CD4+ T-lymphocytes
hepatitis B virus
HIV
Serological markers
title Seroprevalence of hepatitis B virus co-infection among HIV-1-positive patients in North-Central Nigeria: The urgent need for surveillance
title_full Seroprevalence of hepatitis B virus co-infection among HIV-1-positive patients in North-Central Nigeria: The urgent need for surveillance
title_fullStr Seroprevalence of hepatitis B virus co-infection among HIV-1-positive patients in North-Central Nigeria: The urgent need for surveillance
title_full_unstemmed Seroprevalence of hepatitis B virus co-infection among HIV-1-positive patients in North-Central Nigeria: The urgent need for surveillance
title_short Seroprevalence of hepatitis B virus co-infection among HIV-1-positive patients in North-Central Nigeria: The urgent need for surveillance
title_sort seroprevalence of hepatitis b virus co infection among hiv 1 positive patients in north central nigeria the urgent need for surveillance
topic Antiretroviral therapy
Alanine aminotransferase
CD4+ T-lymphocytes
hepatitis B virus
HIV
Serological markers
url https://ajlmonline.org/index.php/ajlm/article/view/622
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