The Effect of Residual Renal Function on Clinical and Laboratory Parameters in Peritoneal Dialysis Patients
Aim:To evaluate the effects of residual renal function (RRF) on anemia treatment, phosphorus control and nutritional parameters in peritoneal dialysis (PD) patients.Methods:PD patients were retrospectively analyzed. Besides anthropometric measurements, biochemical measurements, such as residual glom...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Galenos Yayinevi
2020-09-01
|
Series: | Haseki Tıp Bülteni |
Subjects: | |
Online Access: |
http://www.hasekidergisi.com/archives/archive-detail/article-preview/the-effect-of-residual-renal-function-on-clinical-/40230
|
_version_ | 1797910231130308608 |
---|---|
author | İbrahim Halil Düşünceli Metin Ergül Necmi Eren Betül Gönüllü Kalender Erkan Dervişoğlu |
author_facet | İbrahim Halil Düşünceli Metin Ergül Necmi Eren Betül Gönüllü Kalender Erkan Dervişoğlu |
author_sort | İbrahim Halil Düşünceli |
collection | DOAJ |
description | Aim:To evaluate the effects of residual renal function (RRF) on anemia treatment, phosphorus control and nutritional parameters in peritoneal dialysis (PD) patients.Methods:PD patients were retrospectively analyzed. Besides anthropometric measurements, biochemical measurements, such as residual glomerular filtration rate (rGFR), normalized protein catabolic rate (nPCR), hemoglobin (Hb), serum albumin, calcium, phosphorus, ferritin, parathormone and C-reactive protein levels were recorded.Results:One hundred and fifteen patients (52 females, 63 males; mean age: 56.0±13.2 years 20-83 years) receiving PD treatment were analyzed. The patients were divided into two groups according to presence or absence of RRF (n=75 and n=40, respectively). Patients with RRF had higher body weight (80±14 kg vs 68±13 kg; p<0.001), body mass index (29±5 kg/m² vs 25±5 kg/m²; p=0.009) and serum albumin level (3.6±0.5 vs 3.4±0.5 g/dL; p=0.027]. Patients with RRF had lower erythropoietin [29 (39%), vs. 34 (85%); p<0.001), sevelamer [17 (22.7%) vs 24 (60%); p<0.001] and calcimimetic [9 (12%) vs 14 (35%); p=0.007] usage rates and lower ferritin [159 (88-259) ng/mL vs 323 (170-495) ng/mL; p=0.001] level. rGFR was found to be positively correlated with Hb (r=0.274; p=0.017) and nPCR in patients with RRF (r=0.251; p=0.030).Conclusion:In our study, the positive effects of RRF on the treatment of anemia, phosphorus control and nutritional status in PD patients were shown. |
first_indexed | 2024-04-10T11:21:03Z |
format | Article |
id | doaj.art-46728fbf009245f0967f2af769998ba8 |
institution | Directory Open Access Journal |
issn | 1302-0072 2147-2688 |
language | English |
last_indexed | 2024-04-10T11:21:03Z |
publishDate | 2020-09-01 |
publisher | Galenos Yayinevi |
record_format | Article |
series | Haseki Tıp Bülteni |
spelling | doaj.art-46728fbf009245f0967f2af769998ba82023-02-15T16:18:39ZengGalenos YayineviHaseki Tıp Bülteni1302-00722147-26882020-09-0158434435010.4274/haseki.galenos.2020.609113049054The Effect of Residual Renal Function on Clinical and Laboratory Parameters in Peritoneal Dialysis Patientsİbrahim Halil Düşünceli0Metin Ergül1Necmi Eren2Betül Gönüllü Kalender3Erkan Dervişoğlu4 Kocaeli Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Kocaeli, Türkiye Kocaeli Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Nefroloji Bilim Dalı, Kocaeli, Türkiye Kocaeli Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Nefroloji Bilim Dalı, Kocaeli, Türkiye Kocaeli Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Nefroloji Bilim Dalı, Kocaeli, Türkiye Kocaeli Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Nefroloji Bilim Dalı, Kocaeli, Türkiye Aim:To evaluate the effects of residual renal function (RRF) on anemia treatment, phosphorus control and nutritional parameters in peritoneal dialysis (PD) patients.Methods:PD patients were retrospectively analyzed. Besides anthropometric measurements, biochemical measurements, such as residual glomerular filtration rate (rGFR), normalized protein catabolic rate (nPCR), hemoglobin (Hb), serum albumin, calcium, phosphorus, ferritin, parathormone and C-reactive protein levels were recorded.Results:One hundred and fifteen patients (52 females, 63 males; mean age: 56.0±13.2 years 20-83 years) receiving PD treatment were analyzed. The patients were divided into two groups according to presence or absence of RRF (n=75 and n=40, respectively). Patients with RRF had higher body weight (80±14 kg vs 68±13 kg; p<0.001), body mass index (29±5 kg/m² vs 25±5 kg/m²; p=0.009) and serum albumin level (3.6±0.5 vs 3.4±0.5 g/dL; p=0.027]. Patients with RRF had lower erythropoietin [29 (39%), vs. 34 (85%); p<0.001), sevelamer [17 (22.7%) vs 24 (60%); p<0.001] and calcimimetic [9 (12%) vs 14 (35%); p=0.007] usage rates and lower ferritin [159 (88-259) ng/mL vs 323 (170-495) ng/mL; p=0.001] level. rGFR was found to be positively correlated with Hb (r=0.274; p=0.017) and nPCR in patients with RRF (r=0.251; p=0.030).Conclusion:In our study, the positive effects of RRF on the treatment of anemia, phosphorus control and nutritional status in PD patients were shown. http://www.hasekidergisi.com/archives/archive-detail/article-preview/the-effect-of-residual-renal-function-on-clinical-/40230 albuminhemoglobinperitoneal dialysisresidual renal function |
spellingShingle | İbrahim Halil Düşünceli Metin Ergül Necmi Eren Betül Gönüllü Kalender Erkan Dervişoğlu The Effect of Residual Renal Function on Clinical and Laboratory Parameters in Peritoneal Dialysis Patients Haseki Tıp Bülteni albumin hemoglobin peritoneal dialysis residual renal function |
title | The Effect of Residual Renal Function on Clinical and Laboratory Parameters in Peritoneal Dialysis Patients |
title_full | The Effect of Residual Renal Function on Clinical and Laboratory Parameters in Peritoneal Dialysis Patients |
title_fullStr | The Effect of Residual Renal Function on Clinical and Laboratory Parameters in Peritoneal Dialysis Patients |
title_full_unstemmed | The Effect of Residual Renal Function on Clinical and Laboratory Parameters in Peritoneal Dialysis Patients |
title_short | The Effect of Residual Renal Function on Clinical and Laboratory Parameters in Peritoneal Dialysis Patients |
title_sort | effect of residual renal function on clinical and laboratory parameters in peritoneal dialysis patients |
topic | albumin hemoglobin peritoneal dialysis residual renal function |
url |
http://www.hasekidergisi.com/archives/archive-detail/article-preview/the-effect-of-residual-renal-function-on-clinical-/40230
|
work_keys_str_mv | AT ibrahimhalildusunceli theeffectofresidualrenalfunctiononclinicalandlaboratoryparametersinperitonealdialysispatients AT metinergul theeffectofresidualrenalfunctiononclinicalandlaboratoryparametersinperitonealdialysispatients AT necmieren theeffectofresidualrenalfunctiononclinicalandlaboratoryparametersinperitonealdialysispatients AT betulgonullukalender theeffectofresidualrenalfunctiononclinicalandlaboratoryparametersinperitonealdialysispatients AT erkandervisoglu theeffectofresidualrenalfunctiononclinicalandlaboratoryparametersinperitonealdialysispatients AT ibrahimhalildusunceli effectofresidualrenalfunctiononclinicalandlaboratoryparametersinperitonealdialysispatients AT metinergul effectofresidualrenalfunctiononclinicalandlaboratoryparametersinperitonealdialysispatients AT necmieren effectofresidualrenalfunctiononclinicalandlaboratoryparametersinperitonealdialysispatients AT betulgonullukalender effectofresidualrenalfunctiononclinicalandlaboratoryparametersinperitonealdialysispatients AT erkandervisoglu effectofresidualrenalfunctiononclinicalandlaboratoryparametersinperitonealdialysispatients |