The Effect of Residual Renal Function on Clinical and Laboratory Parameters in Peritoneal Dialysis Patients

Aim:To evaluate the effects of residual renal function (RRF) on anemia treatment, phosphorus control and nutritional parameters in peritoneal dialysis (PD) patients.Methods:PD patients were retrospectively analyzed. Besides anthropometric measurements, biochemical measurements, such as residual glom...

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Main Authors: İbrahim Halil Düşünceli, Metin Ergül, Necmi Eren, Betül Gönüllü Kalender, Erkan Dervişoğlu
Format: Article
Language:English
Published: Galenos Yayinevi 2020-09-01
Series:Haseki Tıp Bülteni
Subjects:
Online Access: http://www.hasekidergisi.com/archives/archive-detail/article-preview/the-effect-of-residual-renal-function-on-clinical-/40230
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author İbrahim Halil Düşünceli
Metin Ergül
Necmi Eren
Betül Gönüllü Kalender
Erkan Dervişoğlu
author_facet İbrahim Halil Düşünceli
Metin Ergül
Necmi Eren
Betül Gönüllü Kalender
Erkan Dervişoğlu
author_sort İbrahim Halil Düşünceli
collection DOAJ
description Aim:To evaluate the effects of residual renal function (RRF) on anemia treatment, phosphorus control and nutritional parameters in peritoneal dialysis (PD) patients.Methods:PD patients were retrospectively analyzed. Besides anthropometric measurements, biochemical measurements, such as residual glomerular filtration rate (rGFR), normalized protein catabolic rate (nPCR), hemoglobin (Hb), serum albumin, calcium, phosphorus, ferritin, parathormone and C-reactive protein levels were recorded.Results:One hundred and fifteen patients (52 females, 63 males; mean age: 56.0±13.2 years 20-83 years) receiving PD treatment were analyzed. The patients were divided into two groups according to presence or absence of RRF (n=75 and n=40, respectively). Patients with RRF had higher body weight (80±14 kg vs 68±13 kg; p<0.001), body mass index (29±5 kg/m² vs 25±5 kg/m²; p=0.009) and serum albumin level (3.6±0.5 vs 3.4±0.5 g/dL; p=0.027]. Patients with RRF had lower erythropoietin [29 (39%), vs. 34 (85%); p<0.001), sevelamer [17 (22.7%) vs 24 (60%); p<0.001] and calcimimetic [9 (12%) vs 14 (35%); p=0.007] usage rates and lower ferritin [159 (88-259) ng/mL vs 323 (170-495) ng/mL; p=0.001] level. rGFR was found to be positively correlated with Hb (r=0.274; p=0.017) and nPCR in patients with RRF (r=0.251; p=0.030).Conclusion:In our study, the positive effects of RRF on the treatment of anemia, phosphorus control and nutritional status in PD patients were shown.
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spelling doaj.art-46728fbf009245f0967f2af769998ba82023-02-15T16:18:39ZengGalenos YayineviHaseki Tıp Bülteni1302-00722147-26882020-09-0158434435010.4274/haseki.galenos.2020.609113049054The Effect of Residual Renal Function on Clinical and Laboratory Parameters in Peritoneal Dialysis Patientsİbrahim Halil Düşünceli0Metin Ergül1Necmi Eren2Betül Gönüllü Kalender3Erkan Dervişoğlu4 Kocaeli Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Kocaeli, Türkiye Kocaeli Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Nefroloji Bilim Dalı, Kocaeli, Türkiye Kocaeli Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Nefroloji Bilim Dalı, Kocaeli, Türkiye Kocaeli Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Nefroloji Bilim Dalı, Kocaeli, Türkiye Kocaeli Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Nefroloji Bilim Dalı, Kocaeli, Türkiye Aim:To evaluate the effects of residual renal function (RRF) on anemia treatment, phosphorus control and nutritional parameters in peritoneal dialysis (PD) patients.Methods:PD patients were retrospectively analyzed. Besides anthropometric measurements, biochemical measurements, such as residual glomerular filtration rate (rGFR), normalized protein catabolic rate (nPCR), hemoglobin (Hb), serum albumin, calcium, phosphorus, ferritin, parathormone and C-reactive protein levels were recorded.Results:One hundred and fifteen patients (52 females, 63 males; mean age: 56.0±13.2 years 20-83 years) receiving PD treatment were analyzed. The patients were divided into two groups according to presence or absence of RRF (n=75 and n=40, respectively). Patients with RRF had higher body weight (80±14 kg vs 68±13 kg; p<0.001), body mass index (29±5 kg/m² vs 25±5 kg/m²; p=0.009) and serum albumin level (3.6±0.5 vs 3.4±0.5 g/dL; p=0.027]. Patients with RRF had lower erythropoietin [29 (39%), vs. 34 (85%); p<0.001), sevelamer [17 (22.7%) vs 24 (60%); p<0.001] and calcimimetic [9 (12%) vs 14 (35%); p=0.007] usage rates and lower ferritin [159 (88-259) ng/mL vs 323 (170-495) ng/mL; p=0.001] level. rGFR was found to be positively correlated with Hb (r=0.274; p=0.017) and nPCR in patients with RRF (r=0.251; p=0.030).Conclusion:In our study, the positive effects of RRF on the treatment of anemia, phosphorus control and nutritional status in PD patients were shown. http://www.hasekidergisi.com/archives/archive-detail/article-preview/the-effect-of-residual-renal-function-on-clinical-/40230 albuminhemoglobinperitoneal dialysisresidual renal function
spellingShingle İbrahim Halil Düşünceli
Metin Ergül
Necmi Eren
Betül Gönüllü Kalender
Erkan Dervişoğlu
The Effect of Residual Renal Function on Clinical and Laboratory Parameters in Peritoneal Dialysis Patients
Haseki Tıp Bülteni
albumin
hemoglobin
peritoneal dialysis
residual renal function
title The Effect of Residual Renal Function on Clinical and Laboratory Parameters in Peritoneal Dialysis Patients
title_full The Effect of Residual Renal Function on Clinical and Laboratory Parameters in Peritoneal Dialysis Patients
title_fullStr The Effect of Residual Renal Function on Clinical and Laboratory Parameters in Peritoneal Dialysis Patients
title_full_unstemmed The Effect of Residual Renal Function on Clinical and Laboratory Parameters in Peritoneal Dialysis Patients
title_short The Effect of Residual Renal Function on Clinical and Laboratory Parameters in Peritoneal Dialysis Patients
title_sort effect of residual renal function on clinical and laboratory parameters in peritoneal dialysis patients
topic albumin
hemoglobin
peritoneal dialysis
residual renal function
url http://www.hasekidergisi.com/archives/archive-detail/article-preview/the-effect-of-residual-renal-function-on-clinical-/40230
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