Clinical analysis of 23 cases of adult reversible splenial lesion syndrome
Objective To analyze the clinical features and mechanism of reversible splenial lesion syndrome (RESLES) in adults. Methods and Results Twenty ⁃ three patients with reversible splenial lesion syndrome diagnosed and treated in the First Affiliated Hospital of Nanchang University from January 2017 to...
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| Format: | Article |
| Language: | English |
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Tianjin Huanhu Hospital
2021-08-01
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| Series: | Chinese Journal of Contemporary Neurology and Neurosurgery |
| Subjects: | |
| Online Access: | http://www.cjcnn.org/index.php/cjcnn/article/view/2382 |
| _version_ | 1818913065592160256 |
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| author | TU Qi WU Cheng⁃si |
| author_facet | TU Qi WU Cheng⁃si |
| author_sort | TU Qi |
| collection | DOAJ |
| description | Objective To analyze the clinical features and mechanism of reversible splenial lesion syndrome (RESLES) in adults. Methods and Results Twenty ⁃ three patients with reversible splenial lesion syndrome diagnosed and treated in the First Affiliated Hospital of Nanchang University from January 2017 to May 2019 were included. The clinical manifestations were headache, dizziness, fever, convulsions, disturbance of consciousness, all 23 patients in this group had decreased serum albumin levels. The common feature of head MRI was a reversible isolated lesion of the corpus callosum, which was round ⁃ shaped with clear borders, with high signal on T2WI, low signal on T1WI, high signal on DWI, and low signal on ADC, and the lesions gradually or completely disappeared on the 14th day of onset. Conclusions The etiology and clinical manifestations of reversible splenial lesion syndrome are complicated. MRI usually presents a reversible round ⁃ shaped lesion in the corpus callosum. Imaging lesions usually disappear earlier than clinical symptoms. The decrease of serum albumin level may be a risk factor for cytotoxic edema. |
| first_indexed | 2024-12-19T23:24:34Z |
| format | Article |
| id | doaj.art-4673d58aeee54cadabb65dc34e9947e1 |
| institution | Directory Open Access Journal |
| issn | 1672-6731 |
| language | English |
| last_indexed | 2024-12-19T23:24:34Z |
| publishDate | 2021-08-01 |
| publisher | Tianjin Huanhu Hospital |
| record_format | Article |
| series | Chinese Journal of Contemporary Neurology and Neurosurgery |
| spelling | doaj.art-4673d58aeee54cadabb65dc34e9947e12022-12-21T20:01:53ZengTianjin Huanhu HospitalChinese Journal of Contemporary Neurology and Neurosurgery1672-67312021-08-0121868669010.3969/j.issn.1672⁃6731.2021.08.012Clinical analysis of 23 cases of adult reversible splenial lesion syndromeTU Qi0WU Cheng⁃si1Department of Neurology, The First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi, ChinaDepartment of Neurology, The First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi, ChinaObjective To analyze the clinical features and mechanism of reversible splenial lesion syndrome (RESLES) in adults. Methods and Results Twenty ⁃ three patients with reversible splenial lesion syndrome diagnosed and treated in the First Affiliated Hospital of Nanchang University from January 2017 to May 2019 were included. The clinical manifestations were headache, dizziness, fever, convulsions, disturbance of consciousness, all 23 patients in this group had decreased serum albumin levels. The common feature of head MRI was a reversible isolated lesion of the corpus callosum, which was round ⁃ shaped with clear borders, with high signal on T2WI, low signal on T1WI, high signal on DWI, and low signal on ADC, and the lesions gradually or completely disappeared on the 14th day of onset. Conclusions The etiology and clinical manifestations of reversible splenial lesion syndrome are complicated. MRI usually presents a reversible round ⁃ shaped lesion in the corpus callosum. Imaging lesions usually disappear earlier than clinical symptoms. The decrease of serum albumin level may be a risk factor for cytotoxic edema.http://www.cjcnn.org/index.php/cjcnn/article/view/2382corpus callosumserum albuminedemamagnetic resonance imaging |
| spellingShingle | TU Qi WU Cheng⁃si Clinical analysis of 23 cases of adult reversible splenial lesion syndrome Chinese Journal of Contemporary Neurology and Neurosurgery corpus callosum serum albumin edema magnetic resonance imaging |
| title | Clinical analysis of 23 cases of adult reversible splenial lesion syndrome |
| title_full | Clinical analysis of 23 cases of adult reversible splenial lesion syndrome |
| title_fullStr | Clinical analysis of 23 cases of adult reversible splenial lesion syndrome |
| title_full_unstemmed | Clinical analysis of 23 cases of adult reversible splenial lesion syndrome |
| title_short | Clinical analysis of 23 cases of adult reversible splenial lesion syndrome |
| title_sort | clinical analysis of 23 cases of adult reversible splenial lesion syndrome |
| topic | corpus callosum serum albumin edema magnetic resonance imaging |
| url | http://www.cjcnn.org/index.php/cjcnn/article/view/2382 |
| work_keys_str_mv | AT tuqi clinicalanalysisof23casesofadultreversiblespleniallesionsyndrome AT wuchengsi clinicalanalysisof23casesofadultreversiblespleniallesionsyndrome |