Long-term survival in a patient with metastatic HER2+ breast cancer undergoing lapatinib-based therapy for 6 years
We report the case of a patient with HER2-positive breast cancer under adjuvant therapy (chemotherapy and trastuzumab) who developed a recurrence with bone (cervical spine) and lung involvement. After treatment with lapatinib and capecitabine, the patient remained stable with considerable improvemen...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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AboutScience Srl
2018-09-01
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| Series: | AboutOpen |
| Subjects: | |
| Online Access: | https://journals.aboutscience.eu/index.php/aboutopen/article/view/7 |
| _version_ | 1818119767890853888 |
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| author | Salvatore Turano Serafino Conforti |
| author_facet | Salvatore Turano Serafino Conforti |
| author_sort | Salvatore Turano |
| collection | DOAJ |
| description | We report the case of a patient with HER2-positive breast cancer under adjuvant therapy (chemotherapy and trastuzumab) who developed a recurrence with bone (cervical spine) and lung involvement. After treatment with lapatinib and capecitabine, the patient remained stable with considerable improvement of her physical condition. After 6 years she is still in maintenance therapy with lapatinib. This case is among a number of long term surviving and long term responding patients, within an atypical subset of patients with HER2-positive metastatic breast cancer, in the presence of encephalic lesions (Oncology). |
| first_indexed | 2024-12-11T05:15:26Z |
| format | Article |
| id | doaj.art-46776735a73a433283fb47041f6746a3 |
| institution | Directory Open Access Journal |
| issn | 2465-2628 |
| language | English |
| last_indexed | 2024-12-11T05:15:26Z |
| publishDate | 2018-09-01 |
| publisher | AboutScience Srl |
| record_format | Article |
| series | AboutOpen |
| spelling | doaj.art-46776735a73a433283fb47041f6746a32022-12-22T01:19:50ZengAboutScience SrlAboutOpen2465-26282018-09-014110.19156/abtpn.2018.0032Long-term survival in a patient with metastatic HER2+ breast cancer undergoing lapatinib-based therapy for 6 yearsSalvatore Turano0Serafino Conforti1UOC Oncologia Medica, Presidio Ospedaliero “Mariano Santo”, Cosenza (Italy)UOC Oncologia Medica, Presidio Ospedaliero “Mariano Santo”, Cosenza (Italy)We report the case of a patient with HER2-positive breast cancer under adjuvant therapy (chemotherapy and trastuzumab) who developed a recurrence with bone (cervical spine) and lung involvement. After treatment with lapatinib and capecitabine, the patient remained stable with considerable improvement of her physical condition. After 6 years she is still in maintenance therapy with lapatinib. This case is among a number of long term surviving and long term responding patients, within an atypical subset of patients with HER2-positive metastatic breast cancer, in the presence of encephalic lesions (Oncology).https://journals.aboutscience.eu/index.php/aboutopen/article/view/7lapatinibMetastatic breast cancerHER2Long-term survival |
| spellingShingle | Salvatore Turano Serafino Conforti Long-term survival in a patient with metastatic HER2+ breast cancer undergoing lapatinib-based therapy for 6 years AboutOpen lapatinib Metastatic breast cancer HER2 Long-term survival |
| title | Long-term survival in a patient with metastatic HER2+ breast cancer undergoing lapatinib-based therapy for 6 years |
| title_full | Long-term survival in a patient with metastatic HER2+ breast cancer undergoing lapatinib-based therapy for 6 years |
| title_fullStr | Long-term survival in a patient with metastatic HER2+ breast cancer undergoing lapatinib-based therapy for 6 years |
| title_full_unstemmed | Long-term survival in a patient with metastatic HER2+ breast cancer undergoing lapatinib-based therapy for 6 years |
| title_short | Long-term survival in a patient with metastatic HER2+ breast cancer undergoing lapatinib-based therapy for 6 years |
| title_sort | long term survival in a patient with metastatic her2 breast cancer undergoing lapatinib based therapy for 6 years |
| topic | lapatinib Metastatic breast cancer HER2 Long-term survival |
| url | https://journals.aboutscience.eu/index.php/aboutopen/article/view/7 |
| work_keys_str_mv | AT salvatoreturano longtermsurvivalinapatientwithmetastaticher2breastcancerundergoinglapatinibbasedtherapyfor6years AT serafinoconforti longtermsurvivalinapatientwithmetastaticher2breastcancerundergoinglapatinibbasedtherapyfor6years |