Tubercular Lymphadenitis Mimicking Findings of Metastatic Signet Cell Carcinoma in FNAC: A Case Report
Tubercular lymphadenitis is one of the most common extrapulmonary tubercular lesions presented in the Outpatient Department which is commonly diagnosed by Fine needle aspiration cytology. Cytological diagnosis of tuberculosis requires the presence of epithelioid cell granulomas demonstration with or...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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HEAD Nepal
2019-06-01
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| Series: | Nepalese Medical Journal |
| Subjects: | |
| Online Access: | https://www.nepjol.info/index.php/nmj/article/view/24505 |
| _version_ | 1818531088160522240 |
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| author | Nirajan Mainali Niraj Nepal Prabesh Kumar Choudhary Agraj Uprety |
| author_facet | Nirajan Mainali Niraj Nepal Prabesh Kumar Choudhary Agraj Uprety |
| author_sort | Nirajan Mainali |
| collection | DOAJ |
| description | Tubercular lymphadenitis is one of the most common extrapulmonary tubercular lesions presented in the Outpatient Department which is commonly diagnosed by Fine needle aspiration cytology. Cytological diagnosis of tuberculosis requires the presence of epithelioid cell granulomas demonstration with or without Langhan’s giant cells and necrosis. Sometimes, there can a proliferation of signet like cells without granulomas, which in a cervical lymph node can be given a false interpretation of metastatic signet cell carcinoma.
A 35 year female patient with a complaint of cervical lymphadenopathy came to the medical OPD. FNAC was done which showed numerous scattered signet ring cells. However, epithelioid cell granulomas weren’t observed in the smears. Zeihl Neelsen stain for Acid fast bacilli was done but the organism wasn’t appreciated. A biopsy was done and a histopathological slide showed epithelioid cell granulomas and Langhan’s giant cell. Zeihl Neelsen Stain for Acid fast bacilli, which was positive. |
| first_indexed | 2024-12-11T17:27:55Z |
| format | Article |
| id | doaj.art-4679a4a215564b66b95131a44d93a493 |
| institution | Directory Open Access Journal |
| issn | 2631-2093 2645-8586 |
| language | English |
| last_indexed | 2024-12-11T17:27:55Z |
| publishDate | 2019-06-01 |
| publisher | HEAD Nepal |
| record_format | Article |
| series | Nepalese Medical Journal |
| spelling | doaj.art-4679a4a215564b66b95131a44d93a4932022-12-22T00:56:55ZengHEAD NepalNepalese Medical Journal2631-20932645-85862019-06-012119119310.3126/nmj.v2i1.2450524505Tubercular Lymphadenitis Mimicking Findings of Metastatic Signet Cell Carcinoma in FNAC: A Case ReportNirajan Mainali0Niraj Nepal1Prabesh Kumar Choudhary2Agraj Uprety3Nobel Medical College Teaching Hospital and Research Centre, Biratnagar, NepalNobel Medical College Teaching Hospital and Research Centre, Biratnagar, NepalNobel Medical College Teaching Hospital and Research Centre, Biratnagar, NepalNobel Medical College Teaching Hospital and Research Centre, Biratnagar, NepalTubercular lymphadenitis is one of the most common extrapulmonary tubercular lesions presented in the Outpatient Department which is commonly diagnosed by Fine needle aspiration cytology. Cytological diagnosis of tuberculosis requires the presence of epithelioid cell granulomas demonstration with or without Langhan’s giant cells and necrosis. Sometimes, there can a proliferation of signet like cells without granulomas, which in a cervical lymph node can be given a false interpretation of metastatic signet cell carcinoma. A 35 year female patient with a complaint of cervical lymphadenopathy came to the medical OPD. FNAC was done which showed numerous scattered signet ring cells. However, epithelioid cell granulomas weren’t observed in the smears. Zeihl Neelsen stain for Acid fast bacilli was done but the organism wasn’t appreciated. A biopsy was done and a histopathological slide showed epithelioid cell granulomas and Langhan’s giant cell. Zeihl Neelsen Stain for Acid fast bacilli, which was positive.https://www.nepjol.info/index.php/nmj/article/view/24505Lymphadenitis; Tuberculosis; Signet ringLymphadenitisTuberculosisSignet cell carcinoma |
| spellingShingle | Nirajan Mainali Niraj Nepal Prabesh Kumar Choudhary Agraj Uprety Tubercular Lymphadenitis Mimicking Findings of Metastatic Signet Cell Carcinoma in FNAC: A Case Report Nepalese Medical Journal Lymphadenitis; Tuberculosis; Signet ring Lymphadenitis Tuberculosis Signet cell carcinoma |
| title | Tubercular Lymphadenitis Mimicking Findings of Metastatic Signet Cell Carcinoma in FNAC: A Case Report |
| title_full | Tubercular Lymphadenitis Mimicking Findings of Metastatic Signet Cell Carcinoma in FNAC: A Case Report |
| title_fullStr | Tubercular Lymphadenitis Mimicking Findings of Metastatic Signet Cell Carcinoma in FNAC: A Case Report |
| title_full_unstemmed | Tubercular Lymphadenitis Mimicking Findings of Metastatic Signet Cell Carcinoma in FNAC: A Case Report |
| title_short | Tubercular Lymphadenitis Mimicking Findings of Metastatic Signet Cell Carcinoma in FNAC: A Case Report |
| title_sort | tubercular lymphadenitis mimicking findings of metastatic signet cell carcinoma in fnac a case report |
| topic | Lymphadenitis; Tuberculosis; Signet ring Lymphadenitis Tuberculosis Signet cell carcinoma |
| url | https://www.nepjol.info/index.php/nmj/article/view/24505 |
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