A retrospective case-control study to evaluate the use of beta-lactam desensitization in the management of penicillin-allergic patients: a potential strategy for Antimicrobial Stewardship Programs

A retrospective case-control study to evaluate the use of beta-lactam desensitization in the management of penicillin-allergic patients: a potential strategy for Antimicrobial Stewardship Programs

Introduction: Penicillin allergy labels (PAL) are common in the hospital setting and are associated with worse clinical outcomes. Desensitization can be a useful strategy for allergic patients when alternative options are suboptimal or not available. The aim was to compare clinical outcomes of patie...

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Main Authors: Alicia Rodríguez-Alarcón, Manuela Sanz de Mena, Soukaina Sara Alanti, Daniel Echeverría-Esnal, Luisa Sorli, Elena Sendra, Adela Benítez-Cano, Estela Membrilla, Francesc Cots, Robert Güerri-Fernández, Ramón Adalia, Juan Pablo Horcajada, Fernando Escolano, Santiago Grau, Silvia Gómez-Zorrilla
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Pharmacology
Subjects:
antibiotic desensitization
penicillins
beta-lactams
antimicrobial stewardship programs
hypersensitivity
allergy
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1260632/full

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