Excess Mortality in Aspirin and Dipyrone (Metamizole) Co‐Medicated Patients With Cardiovascular Disease: A Nationwide Study

Excess Mortality in Aspirin and Dipyrone (Metamizole) Co‐Medicated Patients With Cardiovascular Disease: A Nationwide Study

Background Pain is a major issue in our aging society. Dipyrone (metamizole) is one of the most frequently used analgesics. Additionally, it has been shown to impair pharmacodynamic response to aspirin as measured by platelet function tests. However, it is not known how this laboratory effect transl...

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Bibliographic Details
Main Authors: Amin Polzin, Lisa Dannenberg, Carolin Helten, Martin Pöhl, Daniel Metzen, Philipp Mourikis, Christof Dücker, Ursula Marschall, Helmut L’Hoest, Beata Hennig, Saif Zako, Kajetan Trojovsky, Tobias Petzold, Christian Jung, Bodo Levkau, Tobias Zeus, Karsten Schrör, Thomas Hohlfeld, Malte Kelm
Format: Article
Language:English
Published: Wiley 2021-11-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
aggregation
aspirin
co‐medication
dipyrone
platelet activation
platelet inhibition
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.121.022299

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