Continuous Detection of Increasing Concentrations of Thrombin Employing a Label-Free Photonic Crystal Aptasensor
Thrombin generation is a complex and finely regulated pathway that provokes dynamical changes of thrombin concentration in blood when a vascular injury occurs. In order to characterize the initiation phase of such process, when thrombin concentration is in the nM range, a label-free optical aptasens...
Main Authors: | Paula Martínez-Pérez, Maribel Gómez-Gómez, Todora Angelova, Amadeu Griol, Juan Hurtado, Laurent Bellieres, Jaime García-Rupérez |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-04-01
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Series: | Micromachines |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-666X/11/5/464 |
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