Membranoproliferative glomerulonephritis secondary to chronic myeloid leukemia
The nephrotic syndrome (NS) is a well documented complication of hematological malignancies. However, chronic myeloid leukemia (CML) is rarely complicated by the NS, and it occurs usually after allogenic stem cell transplantation or interferon alpha therapy for CML. The NS as a complication of untre...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2010-01-01
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| Series: | Saudi Journal of Kidney Diseases and Transplantation |
| Online Access: | http://www.sjkdt.org/article.asp?issn=1319-2442;year=2010;volume=21;issue=4;spage=738;epage=741;aulast=Subramanian |
| _version_ | 1818897336368103424 |
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| author | Subramanian Murali Kilara Nalini Manjunath R Mysorekar Vijaya |
| author_facet | Subramanian Murali Kilara Nalini Manjunath R Mysorekar Vijaya |
| author_sort | Subramanian Murali |
| collection | DOAJ |
| description | The nephrotic syndrome (NS) is a well documented complication of hematological malignancies. However, chronic myeloid leukemia (CML) is rarely complicated by the NS, and it occurs usually after allogenic stem cell transplantation or interferon alpha therapy for CML. The NS as a complication of untreated CML is also rare. We report a 31-year-old patient who pre-sented with features of The NS. He was diagnosed to have CML one year ago and was on irre-gular treatment with imatinib mesylate. The renal biopsy and immunofluorescence revealed mem-branoproliferative glomerulonephritis type I. The patient was retreated with imatinib mesylate and the NS resolved gradually over three months. This maybe the third case in literature of mem-branoproliferative glomerulonephritis associated with CML. |
| first_indexed | 2024-12-19T19:14:33Z |
| format | Article |
| id | doaj.art-46895a6f1f034a699777dfd91a7fe6d0 |
| institution | Directory Open Access Journal |
| issn | 1319-2442 |
| language | English |
| last_indexed | 2024-12-19T19:14:33Z |
| publishDate | 2010-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Saudi Journal of Kidney Diseases and Transplantation |
| spelling | doaj.art-46895a6f1f034a699777dfd91a7fe6d02022-12-21T20:09:10ZengWolters Kluwer Medknow PublicationsSaudi Journal of Kidney Diseases and Transplantation1319-24422010-01-01214738741Membranoproliferative glomerulonephritis secondary to chronic myeloid leukemiaSubramanian MuraliKilara NaliniManjunath RMysorekar VijayaThe nephrotic syndrome (NS) is a well documented complication of hematological malignancies. However, chronic myeloid leukemia (CML) is rarely complicated by the NS, and it occurs usually after allogenic stem cell transplantation or interferon alpha therapy for CML. The NS as a complication of untreated CML is also rare. We report a 31-year-old patient who pre-sented with features of The NS. He was diagnosed to have CML one year ago and was on irre-gular treatment with imatinib mesylate. The renal biopsy and immunofluorescence revealed mem-branoproliferative glomerulonephritis type I. The patient was retreated with imatinib mesylate and the NS resolved gradually over three months. This maybe the third case in literature of mem-branoproliferative glomerulonephritis associated with CML.http://www.sjkdt.org/article.asp?issn=1319-2442;year=2010;volume=21;issue=4;spage=738;epage=741;aulast=Subramanian |
| spellingShingle | Subramanian Murali Kilara Nalini Manjunath R Mysorekar Vijaya Membranoproliferative glomerulonephritis secondary to chronic myeloid leukemia Saudi Journal of Kidney Diseases and Transplantation |
| title | Membranoproliferative glomerulonephritis secondary to chronic myeloid leukemia |
| title_full | Membranoproliferative glomerulonephritis secondary to chronic myeloid leukemia |
| title_fullStr | Membranoproliferative glomerulonephritis secondary to chronic myeloid leukemia |
| title_full_unstemmed | Membranoproliferative glomerulonephritis secondary to chronic myeloid leukemia |
| title_short | Membranoproliferative glomerulonephritis secondary to chronic myeloid leukemia |
| title_sort | membranoproliferative glomerulonephritis secondary to chronic myeloid leukemia |
| url | http://www.sjkdt.org/article.asp?issn=1319-2442;year=2010;volume=21;issue=4;spage=738;epage=741;aulast=Subramanian |
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