Kynurenine Pathway Regulation at Its Critical Junctions with Fluctuation of Tryptophan

Kynurenine Pathway Regulation at Its Critical Junctions with Fluctuation of Tryptophan

The kynurenine pathway (KP) is the primary route for the catabolism of the essential amino acid tryptophan. The central KP metabolites are neurologically active molecules or biosynthetic precursors to critical molecules, such as NAD<sup>+</sup>. Within this pathway are three enzymes of i...

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Bibliographic Details
Main Authors: Ashley Newton, Luree McCann, Lu Huo, Aimin Liu
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Metabolites
Subjects:
tryptophan metabolism
enzyme complexation
protein structure
protein–protein interaction
enzymology
catabolic pathway
Online Access:https://www.mdpi.com/2218-1989/13/4/500

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