Comparative study of bone marrow aspiration and needle biopsy for stainable Iron

The amount of stainable Iron in the bone marrow is frequently used as a means of assessing Iron stores. In our study marrow Iron assessed in needle biopsy sections and simultaneously obtained aspirated smears from 75 patients. Significantly different amounts of stainable Iron were observed in needle...

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Main Author: Azarhoush R (MD)
Format: Article
Language:fas
Published: Golestan University of Medical Sciences 1999-03-01
Series:مجله دانشگاه علوم پزشکی گرگان
Subjects:
Online Access:http://goums.ac.ir/journal/browse.php?a_code=A-10-1-374&slc_lang=en&sid=1
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author Azarhoush R (MD)
author_facet Azarhoush R (MD)
author_sort Azarhoush R (MD)
collection DOAJ
description The amount of stainable Iron in the bone marrow is frequently used as a means of assessing Iron stores. In our study marrow Iron assessed in needle biopsy sections and simultaneously obtained aspirated smears from 75 patients. Significantly different amounts of stainable Iron were observed in needle biopsy and aspirated smears in 53.3% of the specimen. The usual difference consisted of significantly less stainable Iron in needle biopsy sections as compared to the aspirated smears (49.3%). In according to this study, in comparison of needle biopsy section to aspirated smears (As a golden test), sensitivity and specificity were 88 and 64 percent, respectively. Also, positive and negative predictive values were 56.5 and 91%, respectively. It can be appreciated that marrow assessment of Iron content may be associated with distinct differences between the needle biopsy specimens, and the aspirated smears, and could lead to diagnostic error, although, with some limitations and cautions biopsy specimen can be used for Iron assessment.
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spelling doaj.art-468d05572b864838b28b3f0325a6dc2e2022-12-22T03:21:29ZfasGolestan University of Medical Sciencesمجله دانشگاه علوم پزشکی گرگان1562-47652008-40801999-03-01114955Comparative study of bone marrow aspiration and needle biopsy for stainable IronAzarhoush R (MD)0 The amount of stainable Iron in the bone marrow is frequently used as a means of assessing Iron stores. In our study marrow Iron assessed in needle biopsy sections and simultaneously obtained aspirated smears from 75 patients. Significantly different amounts of stainable Iron were observed in needle biopsy and aspirated smears in 53.3% of the specimen. The usual difference consisted of significantly less stainable Iron in needle biopsy sections as compared to the aspirated smears (49.3%). In according to this study, in comparison of needle biopsy section to aspirated smears (As a golden test), sensitivity and specificity were 88 and 64 percent, respectively. Also, positive and negative predictive values were 56.5 and 91%, respectively. It can be appreciated that marrow assessment of Iron content may be associated with distinct differences between the needle biopsy specimens, and the aspirated smears, and could lead to diagnostic error, although, with some limitations and cautions biopsy specimen can be used for Iron assessment.http://goums.ac.ir/journal/browse.php?a_code=A-10-1-374&slc_lang=en&sid=1Bone marrowBiopsyAspirationStainable iron
spellingShingle Azarhoush R (MD)
Comparative study of bone marrow aspiration and needle biopsy for stainable Iron
مجله دانشگاه علوم پزشکی گرگان
Bone marrow
Biopsy
Aspiration
Stainable iron
title Comparative study of bone marrow aspiration and needle biopsy for stainable Iron
title_full Comparative study of bone marrow aspiration and needle biopsy for stainable Iron
title_fullStr Comparative study of bone marrow aspiration and needle biopsy for stainable Iron
title_full_unstemmed Comparative study of bone marrow aspiration and needle biopsy for stainable Iron
title_short Comparative study of bone marrow aspiration and needle biopsy for stainable Iron
title_sort comparative study of bone marrow aspiration and needle biopsy for stainable iron
topic Bone marrow
Biopsy
Aspiration
Stainable iron
url http://goums.ac.ir/journal/browse.php?a_code=A-10-1-374&slc_lang=en&sid=1
work_keys_str_mv AT azarhoushrmd comparativestudyofbonemarrowaspirationandneedlebiopsyforstainableiron