An Overview of Autophagy in Helicobacter pylori Infection and Related Gastric Cancer
Helicobacter pylori (H. pylori) infection is considered a class I carcinogen in the pathogenesis of gastric cancer. In recent years, the interaction relationship between H. pylori infection and autophagy has attracted increasing attention. Most investigators believe that the pathogenesis of gastric...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-04-01
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| Series: | Frontiers in Cellular and Infection Microbiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fcimb.2022.847716/full |
| _version_ | 1819045340432564224 |
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| author | Yihan Yang Xu Shu Chuan Xie |
| author_facet | Yihan Yang Xu Shu Chuan Xie |
| author_sort | Yihan Yang |
| collection | DOAJ |
| description | Helicobacter pylori (H. pylori) infection is considered a class I carcinogen in the pathogenesis of gastric cancer. In recent years, the interaction relationship between H. pylori infection and autophagy has attracted increasing attention. Most investigators believe that the pathogenesis of gastric cancer is closely related to the formation of an autophagosome-mediated downstream signaling pathway by H. pylori infection-induced cells. Autophagy is involved in H. pylori infection and affects the occurrence and development of gastric cancer. In this paper, the possible mechanism by which H. pylori infection affects autophagy and the progression of related gastric cancer signaling pathways are reviewed. |
| first_indexed | 2024-12-21T10:27:01Z |
| format | Article |
| id | doaj.art-468db31ce35c40df912997365eb60b69 |
| institution | Directory Open Access Journal |
| issn | 2235-2988 |
| language | English |
| last_indexed | 2024-12-21T10:27:01Z |
| publishDate | 2022-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cellular and Infection Microbiology |
| spelling | doaj.art-468db31ce35c40df912997365eb60b692022-12-21T19:07:18ZengFrontiers Media S.A.Frontiers in Cellular and Infection Microbiology2235-29882022-04-011210.3389/fcimb.2022.847716847716An Overview of Autophagy in Helicobacter pylori Infection and Related Gastric CancerYihan YangXu ShuChuan XieHelicobacter pylori (H. pylori) infection is considered a class I carcinogen in the pathogenesis of gastric cancer. In recent years, the interaction relationship between H. pylori infection and autophagy has attracted increasing attention. Most investigators believe that the pathogenesis of gastric cancer is closely related to the formation of an autophagosome-mediated downstream signaling pathway by H. pylori infection-induced cells. Autophagy is involved in H. pylori infection and affects the occurrence and development of gastric cancer. In this paper, the possible mechanism by which H. pylori infection affects autophagy and the progression of related gastric cancer signaling pathways are reviewed.https://www.frontiersin.org/articles/10.3389/fcimb.2022.847716/fullautophagyHelicobacter pylorigastric cancersignaling pathwaystherapy |
| spellingShingle | Yihan Yang Xu Shu Chuan Xie An Overview of Autophagy in Helicobacter pylori Infection and Related Gastric Cancer Frontiers in Cellular and Infection Microbiology autophagy Helicobacter pylori gastric cancer signaling pathways therapy |
| title | An Overview of Autophagy in Helicobacter pylori Infection and Related Gastric Cancer |
| title_full | An Overview of Autophagy in Helicobacter pylori Infection and Related Gastric Cancer |
| title_fullStr | An Overview of Autophagy in Helicobacter pylori Infection and Related Gastric Cancer |
| title_full_unstemmed | An Overview of Autophagy in Helicobacter pylori Infection and Related Gastric Cancer |
| title_short | An Overview of Autophagy in Helicobacter pylori Infection and Related Gastric Cancer |
| title_sort | overview of autophagy in helicobacter pylori infection and related gastric cancer |
| topic | autophagy Helicobacter pylori gastric cancer signaling pathways therapy |
| url | https://www.frontiersin.org/articles/10.3389/fcimb.2022.847716/full |
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